Table 1 Characteristics of AKI patients
Variables | Total (n = 831) | Survival (n = 609) | Mortality (n = 222) | Statistics | P |
|---|---|---|---|---|---|
Age, years, Mean ± SD | 64.61 ± 15.99 | 63.55 ± 16.18 | 67.52 ± 15.10 | t=-3.19 | 0.001 |
Age groups, n (%) | χ2 = 5.44 | 0.020 | |||
Age < 65 | 400 (48.13) | 308 (50.57) | 92 (41.44) | ||
Age ≥ 65 | 431 (51.87) | 301 (49.43) | 130 (58.56) | ||
Gender, n (%) | χ2 = 2.51 | 0.113 | |||
Female | 348 (41.88) | 265 (43.51) | 83 (37.39) | ||
Male | 483 (58.12) | 344 (56.49) | 139 (62.61) | ||
Race, n (%) | χ2 = 17.06 | 0.002 | |||
Asian | 12 (1.44) | 10 (1.64) | 2 (0.90) | ||
White | 576 (69.31) | 437 (71.76) | 139 (62.61) | ||
Black | 54 (6.50) | 43 (7.06) | 11 (4.95) | ||
Hispanic | 21 (2.53) | 17 (2.79) | 4 (1.80) | ||
Others | 168 (20.22) | 102 (16.75) | 66 (29.73) | ||
Mechanical ventilation use, n (%) | χ2 = 10.26 | 0.001 | |||
No | 270 (32.49) | 217 (35.63) | 53 (23.87) | ||
Yes | 561 (67.51) | 392 (64.37) | 169 (76.13) | ||
Vasopressors use, n (%) | χ2 = 41.60 | < 0.001 | |||
No | 416 (50.06) | 346 (56.81) | 70 (31.53) | ||
Yes | 415 (49.94) | 263 (43.19) | 152 (68.47) | ||
Renal replacement therapy, n (%) | χ2 = 2.55 | 0.110 | |||
No | 807 (97.11) | 588 (96.55) | 219 (98.65) | ||
Yes | 24 (2.89) | 21 (3.45) | 3 (1.35) | ||
AKI stage, n (%) | χ2 = 84.21 | < 0.001 | |||
I | 145 (17.45) | 126 (20.69) | 19 (8.56) | ||
II | 370 (44.52) | 308 (50.57) | 62 (27.93) | ||
III | 316 (38.03) | 175 (28.74) | 141 (63.51) | ||
ICU length of stay, day, M (Q1, Q3) | 4.25 (2.50,8.78) | 4.26 (2.58,9.28) | 4.16 (2.23,7.93) | Z=-1.28 | 0.202 |
CCI, M (Q1, Q3) | 2.00 (1.00,4.00) | 2.00 (1.00,4.00) | 3.00 (2.00,5.00) | Z = 5.69 | < 0.001 |
SOFA, M (Q1, Q3) | 6.00 (4.00,9.00) | 6.00 (3.00,8.00) | 8.00 (5.00,11.00) | Z = 8.03 | < 0.001 |
SAPS-II, M (Q1, Q3) | 43.00 (33.00,55.00) | 39.00 (30.00,50.00) | 53.00 (43.00,66.00) | Z = 10.63 | < 0.001 |
GCS, Mean ± SD | 13.57 ± 2.95 | 13.85 ± 2.54 | 12.82 ± 3.76 | t = 3.80 | < 0.001 |
HB, g/dL, Mean ± SD | 10.95 ± 2.20 | 11.11 ± 2.24 | 10.52 ± 2.03 | t = 3.41 | < 0.001 |
RDW, %, Mean ± SD | 15.46 ± 2.32 | 15.18 ± 2.09 | 16.24 ± 2.71 | t=-5.31 | < 0.001 |
AG, mEq/L, Mean ± SD | 15.60 ± 4.75 | 15.16 ± 4.34 | 16.82 ± 5.54 | t=-4.03 | < 0.001 |
eGFR, mL/min/1.73m2, M (Q1, Q3) | 66.81 (37.33,96.98) | 73.41 (42.16,100.45) | 51.00 (31.21,86.23) | Z=-4.84 | < 0.001 |
SpO2, %, Mean ± SD | 96.65 ± 4.36 | 96.87 ± 4.13 | 96.05 ± 4.90 | t = 2.21 | 0.028 |
NLR, M (Q1, Q3) | 9.36 (5.80,17.40) | 8.73 (5.25,15.30) | 11.03 (7.18,21.95) | Z = 3.97 | < 0.001 |
PT, seconds, M (Q1, Q3) | 14.90 (13.50,17.70) | 14.60 (13.40,16.90) | 16.15 (14.10,20.70) | Z = 5.46 | < 0.001 |
INR, M (Q1, Q3) | 1.30 (1.20,1.70) | 1.30 (1.20,1.60) | 1.55 (1.30,2.20) | Z = 5.93 | < 0.001 |
RR, insp/min, Mean ± SD | 20.37 ± 6.40 | 20.09 ± 6.41 | 21.14 ± 6.34 | t=-2.08 | 0.038 |
Height, cm, Mean ± SD | 169.33 ± 14.96 | 169.36 ± 15.88 | 169.24 ± 12.13 | t = 0.11 | 0.912 |
Weight, kg, M (Q1, Q3) | 80.00 (68.00,95.30) | 80.83 (69.35,95.60) | 78.58 (66.45,94.60) | Z=-1.49 | 0.135 |
BMI, kg/m2, M (Q1, Q3) | 27.61 (23.84,33.08) | 27.82 (24.22,33.08) | 26.77 (23.25,33.00) | Z=-1.83 | 0.067 |
Lymphocytes, %, M (Q1, Q3) | 8.60 (5.00,13.20) | 9.10 (5.30,14.00) | 7.70 (4.00,11.00) | Z=-4.03 | < 0.001 |
Neutrophil, %, Mean ± SD | 79.02 ± 15.78 | 78.83 ± 14.95 | 79.55 ± 17.88 | t=-0.54 | 0.592 |
Platelet, K/uL, M (Q1, Q3) | 196.00 (128.00,278.00) | 197.00 (135.00,283.00) | 192.50 (115.00,269.00) | Z=-1.59 | 0.111 |
Glucose, mg/dL, M (Q1, Q3) | 132.00 (107.00,174.00) | 132.00 (107.00,171.00) | 132.50 (107.00,181.00) | Z = 0.48 | 0.633 |
Follow-up time, day, M (Q1, Q3) | 30.00 (23.00,30.00) | 30.00 (30.00,30.00) | 6.00 (2.00,13.00) | Z=-28.36 | < 0.001 |
PNI, n (%) | χ2 = 22.86 | < 0.001 | |||
PNI < 28.5 | 192 (23.10) | 115 (18.88) | 77 (34.68) | ||
PNI ≥ 28.5 | 639 (76.90) | 494 (81.12) | 145 (65.32) | ||
GNRI, n (%) | χ2 = 28.56 | < 0.001 | |||
GNRI < 83.25 | 353 (42.48) | 225 (36.95) | 128 (57.66) | ||
GNRI ≥ 83.25 | 478 (57.52) | 384 (63.05) | 94 (42.34) |