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Table 2 A comparison of participants' response to the PROMPT questionnaire pre- and post MTM-implementation

From: Effect of medication therapy management services on medication-burden quality of life in hemodialysis patients

PROMPT items

Pre MTM

Post MTM

P-value

Median (IQR)

Domain 1: Medicine information and relation with health care providers

  Indications for treating your diseases or relieving the symptoms

  Proper use of medicines

4(2-4)

5(5-5)

<0.001*

  What to do if you missed medicine doses

4(3-4)

5(5-5)

<0.001*

  Side effects possibly caused by your medicines and resolving them

1(1-1)

2(1-4)

<0.001*

  Symptoms, severity, and treatment of the disease

1(1-1)

1(1-3)

<0.001*

  Think the doctor, pharmacist, or nurse have friendly manners and give you an opportunity to ask questions about your medicines?

4(2-4)

5(4-5)

<0.001*

 

4(3-5)

5(3-5)

0.14

  Domain 1 total score (Mean± SD)

45.43±17.66

66.87±17.48

<0.001*

Cohen’s d =1.23

 Domain 2: Medicine effectiveness

  Alleviating the symptoms

3(2-4)

4(3-4)

0.01*

  Curing the disease

3(2-4)

3(2-3)

0.04*

  Domain 2 total score (Mean± SD)

52.04±30.57

52.40±28.09

0.92

Cohen’s d =0.01

 Domain 3: Administration related concern

  Feeling bored or uncomfortable for using your medicines every day

4(2-5)

5(3-5)

0.003*

  Medicine dependance

4(2-5)

5(3-5)

0.06

  Ease of use

4(3-5)

5(4-5)

<0.001*

  Domain 3 total score (Mean± SD)

63.46±29.43

75.72±28.16

<0.001*

Cohen’s d = 0.43

 Domain 4: Medicine problems concern

  Medicines interacting with each other

5(3-5)

5(3-5)

0.15

  Adverse drug effects

4(2-5)

5(4-5)

<0.001*

  Domain 4 total score (Mean± SD)

65.26±30.96

78.73±24.50

<0.001*

Cohen’s d = 0.48

 Domain 5: Impact on patient’s life

  Working, study, household chores, hobbies, or socializing with friends or relatives

  Medicine and travel expenses

4(3-5)

5(3-5)

0.11

  Overall, how do your medicines improve your life?

3(2-5)

3(2-5)

0.1

 

3(3-4)

3(3-4)

0.02*

  Domain 5 total score (Mean± SD)

56.97±21.45

64.02±24.00

0.004*

Cohen’s d = 0.31

 Overall PROMPT score

50.74±9.68

59.3± 9.86

<0.001*

Cohen’s d = 0.88

  1. IQR Interquartile range, SD standard deviation
  2. *Significant (p<0.05)