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Table 3 Comparison of DRPs pre- and post the implementation of MTM

From: Effect of medication therapy management services on medication-burden quality of life in hemodialysis patients

 

Pre MTM

Post MTM

 

No. of events (Percentage out of total number of DRP)

p-value

Untreated indication

56 (4.5%)

47 (5.91%)

0.43

Improper drug selection

22 (1.77%)

14 (1.76%)

0.14

Subtherapeutic dose

27 (2.17%)

9 (1.13%)

0.001*

Failure to receive drug

24 (1.93%)

7 (0.88%)

0.004*

Overdose

39 (3.13%)

16 (2.02%)

0.002*

Adverse effects

1008 (80.96%)

682 (85.89%)

<0.001*

Drug interaction

13 (1.04%)

0 (0%)

0.001*

Drug without indication

20 (1.61%)

10 (1.26%)

0.07

Mode of administration (Timing)

18 (1.45%)

9 (1.13%)

0.05

Duplicate therapy

18 (1.45%)

0 (0%)

0.001*

Total Number of drug related problems

Mean± SD (DRPs/patient) **

(1245)

11.97±4.65

(794)

7.63±3.85

<0.001*

  1. *Significant (p<0.05), **Using paired t-test, Wilcoxon-signed rank was used for the DRPs categories