Table 1 Demographic, clinical characteristics, and outcomes of the patients hospitalized with COVID-19, considering the need for kidney replacement therapy, 2021/2022

Age (years)

59 (48–70)

64 (56–73)

59 (47–70)

 < 0.001

Male

5100 (53.8%)

522 (62.8%)

4548 (52.9)

 < 0.001

Comorbidities

 Hypertension

4928 (52.0%)

532 (64.0%)

4368 (50.8%)

 < 0.001

 Coronary artery disease

389 (4.1%)

45 (5.4%)

344 (4.0%)

0.055

 Heart failure

449 (4.7%)

39 (4.7%)

408 (4.7%)

 > 0.999

 Stroke

251 (2.6%)

15 (1.8%)

235 (2.7%)

0.140

 Asthma

541 (5.7%)

40 (4.8%)

494 (5.8%)

0.307

 COPD

469 (5.0%)

47 (5.7%)

426 (5.0%)

0.361

 Diabetes mellitus

2412 (25.5%)

299 (36.0%)

2101 (24.5%)

 < 0.001

 Obesity

1768 (18.7%)

207 (24.9%)

1547 (18.0%)

 < 0.001

 Cirrhosis

27 (0.3%)

5 (0.6%)

22 (0.3%)

0.084

 Chronic kidney disease

295 (3.1%)

58 (7.0%)

233 (2.7%)

 < 0.001

 HIV infection

65 (0.7%)

8 (1.0%)

60 (0.7%)

0.387

 Cancer

305 (3.2%)

29 (3.5%)

279 (3.2%)

0.683

 Previous transplantation

75 (0.8%)

19 (2.3%)

54 (0.6%)

 < 0.001

Lifestyle habits

 Illicit drugs

59 (0.6%)

2 (0.2%)

56 (0.7%)

0.239

 Alcoholism

552 (5.8%)

41 (4.9%)

512 (6.0%)

0.247

 Current smoker

399 (4.2%)

35 (4.2%)

363 (4.2%)

 > 0.999

Admission data

 Glasgow coma score < 15

452 (4.8%)

39 (4.7%)

408 (4.7%)

 > 0.999

 Systolic blood pressure (mmHg)

125 (116–140)

130 (120–140)

124 (116- 140)

0.005

 Heart rate (bpm1)

85 (76–95)

88 (80–97)

85 (75–95)

 < 0.001

 Respiratory rate (bpm2)

20 (18–24)

24 (20–28)

20 (18–24)

 SpO2/FiO2

350 (290.6–433.3)

339.3 (216.3–423.8)

350.0 (293.8, 438.1)

Outcomes

 Admission to the ICU

3042 (32.1%)

810 (97.5%)

2220 (25.9%)

 < 0.001

 Invasive MV

2272 (24.0%)

779 (93.7%)

1482 (17.3%)

 < 0.001

 In-hospital mortality

1705 (18.0%)

675 (81.2%)

1031 (12.0%)

 < 0.001