Fig. 2
From: Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy
Identification of urinary exosomes and proteomic analysis of proteins related to regulating actin cytoskeleton. (A) Typical TEM images of urinary exosomes (scale bars; a = 100 nm, b = 500 nm). (B) Western blot images of CD9, CD63, TSG101, and Calnexin (The blots were properly cut prior to hybridisation with antibodies during blotting). (C) Hierarchical clustering heatmap analysis of 15 urinary proteins in the three groups. (D) Volcano analysis of urinary exosome proteins between T2DM, and DN groups. The abscissa is represented by fold change and the ordinate is represented by -log10 (P value)