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Table 4 Results of univariate analysis of medication literacy determinants for patients undergoing hemodialysis (N = 290)

From: Prevalence, associated factors and clinical implications of medication literacy linked to frailty in hemodialysis patients in China: a cross-sectional study

Variable name

Inadequate ML (N = 56)

Marginal ML (N = 153)

Adequate ML (N = 81)

Statistic

P

Sex

   

χ 2 = 9.279c

0.01

Male

25

87

57

  

Female

31

66

24

  

Age

   

Fisher = 38.121c

<0.001

<65

29

128

77

  

≥ 65

27

25

4

  

Education level

   

H = 54.893b

<0.001

Primary school or lower

17

79

42

  

Junior high school

2

8

10

  

Senior high school

26

58

28

  

University or higher

11

8

1

  

Monthly income

   

H = 15.902b

<0.001

<3000

30

60

19

  

3000 ~ 8000

19

72

38

  

>8000

7

21

24

  

Primary illness

   

Fisher = 8.582c

0.195

Hypertension

21

65

32

  

Diabetes

11

25

8

  

Others

22

44

30

  

Unknown

2

19

11

  

Take medication with the help of a caregiver

   

χ 2 = 31.013c

<0.001

Yes

25

19

10

  

No

31

134

71

  

Dialysis vintage (yrs)

   

H = 2.633b

0.268

<1

4

20

12

  

1–5

22

66

36

  

>5

30

67

33

  

No. of medications

   

χ 2 = 1.745c

0.418

< 5

29

91

51

  

≥ 5

27

62

30

  

Comorbidity

   

χ 2 = 2.853c

0.240

< 5

37

112

64

  

≥ 5

19

41

17

  

Frailty

   

H = 16.536b

<0.001

non-frail

13

44

29

  

Pre-frail

20

92

43

  

frail

23

17

9

  

Body mass index (BMI),m/kg2

22.45 ± 4.58

22.67 ± 3.21

22.85 ± 3.12

 F = 1.035d

0.482

Laboratory findings

     

Red blood cell count(RBC), ×1012/L

3.78 ± 0.73

3.59 ± 0.67

3.58 ± 0.60

 F = 1.085d

0.317

Hemoglobin(HGB),g/L

109.05 ± 17.02

106.37 ± 17.23

107.78 ± 15.36

 F = 1.203d

0.161

Ferritin(FER), ng/mL

158.95 (67.09, 372.40)a

262.10 (114.50, 445.55)a

216.70 (106.45, 335.30)a

H = 230.583b

0.477

Albumin(ALB), g/L

41.70 (39.37, 44.08)a

43.00 (40.55, 45.65)a

44.20 (41.40, 45.70)a

H = 33.217b

0.156

Pre-dialysis creatinine (pre-CRE), µmol/L

853.43 ± 298.93

945.86 ± 231.35

1049.57 ± 252.12

 F = 0.781d

0.867

β2-microglobulin (β2-MG) mg/L

50.20 (35.85,61.43)a

40.60 (33.96,48.30)a

37.90 (30.78, 46.50)a

H = 90.519b

0.024

Serum calcium (s-Ca), mmol/L

2.22 ± 0.23

2.25 ± 0.22

2.28 ± 0.27

 F = 0.997d

0.496

Serum inorganic phosphorus(s-IP), mmol/L

1.81 (1.38, 2.26)a

1.95(1.65, 2.25)a

2.06 (1.83, 2.32)a

H = 11.357b

0.023

Parathyroid hormone(PTH), pmol/L

42.29 (22.31, 63.49)a

46.21 (29.23, 64.32)a

48.53 (30.57, 65.74)a

H = 107.824b

0.541

Serum potassium(s-K),mmol/L

4.81 (4.36, 5.25)a

4.69 (4.38, 5.15)a

4.71 (4.30, 5.360)a

H = 2.610b

2.610

  1. aNotes: median (IQR)
  2. bKruskal-Wallis H test
  3. cchi-square test
  4. dOne-Way ANOVA.