Table 2 Baseline symptom data (IPOS-Renal)
Variable | Conservative N = 216 | On dialysis N = 123 | p-value |
|---|---|---|---|
Pain (n, %) | 0.013* | ||
Not at all | 86 (42.0%) | 42 (36.2%) | |
Slight/moderate | 80 (39.0%) | 35 (30.2%) | |
Severe/overwhelming | 39 (19.0%) | 39 (33.6%) | |
Shortness of breath (n,%) | 0.35 | ||
Not at all | 88 (43.3%) | 60 (51.7%) | |
Slight/moderate | 90 (44.3%) | 44 (37.9%) | |
Severe/overwhelming | 25 (12.3%) | 12 (10.3%) | |
Lack of energy (n, %) | |||
Not at all | 39 (19.0%) | 15 (12.9%) | 0.27 |
Slight/moderate | 102 (49.8%) | 67 (57.8%) | |
Severe/overwhelming | 64 (31.2%) | 34 (29.3%) | |
Nausea (n, %) | 0.30 | ||
Not at all | 160 (77.3%) | 84 (72.4%) | |
Slight/moderate | 38 (18.4%) | 29 (25.0%) | |
Severe/overwhelming | 9 (4.3%) | 3 (2.6%) | |
Vomiting (n, %) | 0.49 | ||
Not at all | 188 (91.7%) | 103 (88.8%) | |
Slight/moderate | 14 (6.8%) | 12 (10.3%) | |
Severe/overwhelming | 3 (1.5%) | 1 (0.9%) | |
Poor appetite (n, %) | 0.85 | ||
Not at all | 107 (52.2%) | 64 (55.2%) | |
Slight/moderate | 66 (32.2%) | 36 (31.0%) | |
Severe/overwhelming | 32 (15.6%) | 16 (13.8%) | |
Constipation (n, %) | 0.88 | ||
Not at all | 129 (62.9%) | 71 (61.2%) | |
Slight/moderate | 62 (30.2%) | 38 (32.8%) | |
Severe/overwhelming | 14 (6.8%) | 7 (6.0%) | |
Mouth problems (n, %) | 0.10 | ||
Not at all | 82 (41.0%) | 56 (48.7%) | |
Slight/moderate | 84 (42.0%) | 49 (42.6%) | |
Severe/overwhelming | 34 (17.0%) | 10 (8.7%) | |
Drowsiness (n, %) | 0.52 | ||
Not at all | 66 (32.5%) | 41 (35.3%) | |
Slight/moderate | 99 (48.8%) | 59 (50.9%) | |
Severe/overwhelming | 38 (18.7%) | 16 (13.8%) | |
Poor mobility (n, %) | 0.48 | ||
Not at all | 52 (25.4%) | 36 (31.6%) | |
Slight/moderate | 94 (45.9%) | 49 (43.0%) | |
Severe/overwhelming | 59 (28.8%) | 29 (25.4%) | |
Itching (n, %) | |||
Not at all | 84 (40.6%) | 42 (36.5%) | 0.55 |
Slight/moderate | 83 (40.1%) | 45 (39.1%) | |
Severe/overwhelming | 40 (19.3%) | 28 (24.3%) | |
Difficulty sleeping (n, %) | 0.05 | ||
Not at all | 89 (43.2%) | 38 (33.0%) | |
Slight/moderate | 79 (38.3%) | 43 (37.4%) | |
Severe/overwhelming | 38 (18.4%) | 34 (29.6%) | |
Restless legs (n, %) | < 0.001* | ||
Not at all | 152 (75.2%) | 62 (53.4%) | |
Slight/moderate | 40 (19.8%) | 39 (33.6%) | |
Severe/overwhelming | 10 (5.0%) | 15 (12.9%) | |
Skin changes (n, %) | 0.70 | ||
Not at all | 133 (64.3%) | 70 (60.3%) | |
Slight/moderate | 62 (30.0%) | 37 (31.9%) | |
Severe/overwhelming | 12 (5.8%) | 9 (7.8%) | |
Diarrhoea (n, %) | 0.86 | ||
Not at all | 165 (80.5%) | 90 (78.3%) | |
Slight/moderate | 30 (14.6%) | 18 (15.7%) | |
Severe/overwhelming | 10 (4.9%) | 7 (6.1%) | |
Taste changes | 0.37 | ||
Not at all | 93 (64.1%) | 48 (60.8%) | |
Slight/moderate | 37 (25.5%) | 26 (32.9%) | |
Severe/overwhelming | 15 (10.3%) | 5 (6.3%) | |
Additional concern present (n, %) | 39 (18.1%) | 22 (17.9%) | 0.97 |
Feeling anxious (n, %) | 0.12 | ||
Not at all | 80 (41.7%) | 35 (33.7%) | |
Slight/moderate | 76 (39.6%) | 39 (37.5%) | |
Severe/overwhelming | 36 (18.8%) | 30 (28.8%) | |
Feeling depressed (n, %) | 0.52 | ||
Not at all | 96 (50.8%) | 46 (45.1%) | |
Slight/moderate | 71 (37.6%) | 40 (39.2%) | |
Severe/overwhelming | 22 (11.6%) | 16 (15.7%) |