Fig. 1

Managements of the patient prior to and after his transfer to us. Red circle and blue cross denote body temperature and pulse, respectively. The open circles indicate continous monitoring of the vital signs, during which fever was contained by lysine acetylsalicylate. A: the initiation of hemodialysis using femoral catheter. B: onset of fever and replacement of the femoral catheter with a new one to the internal jugular vein. C, D, E: biopsy of the lymph nodes and bone marrow (BM) aspiration, detection of hemophagocytosis in BM and determination of serum CD25 level/NK cell activity, respectively