Skip to main content
Fig. 7 | BMC Nephrology

Fig. 7

From: Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway

Fig. 7

Nrf2 inhibitor abolished the protection of PF on H/R-induced HK-2 cells. (A) The intracellular ROS level was measured by flow cytometry. (B) The intracellular ROS level was detected by using fluorescence microscopy. (C) The data shown are the mean fluorescence intensities analyzed by using the Image J software (n = 3). (D) The SOD activity was detected by using a commercial assay kit. € The MDA level was determined by using commercial assay kits. The values were expressed as the mean ± SD (n = 9). *p < 0.05, ****p < 0.0001, in comparison with the NC group. #p < 0.05, ###p < 0.001, ####p < 0.0001, in comparison with the H/R group. ^p < 0.05, ^^^^p < 0.0001, in comparison with the H/R + PF group. NC, normal control, H/R, hypoxia/reoxygenation, PF, paeoniflorin, SD, standard deviation

Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us