Table 3 The list of the polymorphic gene, the specific single nucleotide polymorphism (SNPs), its particular allele and the odds ratio (OR) that suspected as risk of recurrent urolithiasis
From: Genes polymorphism as risk factor of recurrent urolithiasis: a systematic review and meta-analysis
Author | Polymorphic gene | SNP | Allele 1 (case/control) | Allele 2 (case/control) | OR of Allele 2 | CI | p-value |
|---|---|---|---|---|---|---|---|
Chen WC | Calcitonin receptor | AluI | C (175/204) | T (29/6) | 5.634 [2.286, 13.885] | 95% | < 0.01 |
Shakhssalim (a) | Calcium Sensing Receptor | R990G | R (184/212) | G (14/2) | 8.06 [1.80, 35.9] | 95% | 0.006 |
Shakhssalim (b) | Calcium Sensing Receptor | A986S | A (168/200) | S (30/14) | 2.55 [1.31, 4.96] | 95% | 0.006 |
Lai KC | Interleukin-18 | TaqI | A (266/185) | C (137/23) | 4.14 [2.56, 6.69] | 95% | < 0.001 |
Chen WC | Interleukin-1Ra | VNTR | Type II (3/12) | Type I (293/194) | 9.041 [1.683, 21.687] | 95% | 0.005 |
Esposito T (a) | Melatonin Receptor 1 A | rs13140012 | A (342/317) | T (150/221) | 0.63 [0.49, 0.81] | 95% | 0.0004 |
Esposito T (b) | Melatonin Receptor 1 A | rs6553010 | C (313/383) | T (179/155) | 1.41 [1.09, 1.84] | 95% | 0.009 |
Chou YH | ORAI 1 | rs12313273 | T (62/750) | C (46/250) | 2.23 [1.48, 3.35] | 95% | 0.037 |
Yamate T | Osteopontin | AluI | C (28/38) | T (52/34) | 2.08 [1.08, 3.98] | 95% | < 0.05 |
Huang SH | TAP2-2 | MspI | G (169/246) | A (245/170) | 2.10 [1.59, 2.77] | 95% | < 0.0001 |
Aykan S (b) | Urokinase | ApaLI | C (133/310) | T (23/24) | 2.23 [1.22, 4.10] | 95% | 0.01 |
Tsai FJ | Urokinase | ApaLI | C (288/206) | T (18/4) | 3.088 [1.090, 8.995] | 95% | 0.028 |
Aykan S (a) | Vitamin D receptor | TaqI | T (80/218) | C (76/116) | 1.79 [1.21, 2.63] | 95% | 0.003 |
Rendina D (a) | Vitamin D Receptor | ApaI | A (173/142) | a (145/106) | 1.12 [0.80, 1.57] | 95% | < 0.05 |
Rendina D (b) | Vitamin D Receptor | BsmI | B (163/134) | b (155/114) | 1.12 [0.80, 1.56] | 95% | < 0.05 |
Mossetti G (a) | Vitamin D receptor | TaqI | T (264/136) | t (176/92) | 0.99 [0.71, 1.37] | 95% | < 0.001 |
Mossetti G (b) | Vitamin D receptor | BsmI | B (202/122) | b (238/106) | 1.36 [0.98, 1.87] | 95% | 0.005 |