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Table 1 Baseline characteristics of the patients with acute pancreatitis

From: Construction and validation of a risk assessment model for acute kidney injury in patients with acute pancreatitis in the intensive care unit

Variable

level

Training cohort

Validation cohort

P value

  

674

289

 

Gender (%)

M

402 (59.6)

165 (57.1)

0.51

 

F

272 (40.4)

124 (42.9)

Age (years) (%)

< 65

434 (64.4)

170 (58.8)

0.12

 

>=65

240 (35.6)

119 (41.2)

Weight (kg)

83.33 [71.15, 100.84]

80.10 [70.00, 98.50]

0.09

Antibiotic (%)

no

192 (28.5)

88 (30.5)

0.60

 

yes

482 (71.5)

201 (69.5)

Hypertension (%)

no

558 (82.8)

249 (86.2)

0.23

 

yes

116 (17.2)

40 (13.8)

 

Alcohol abuse(%)

no

485 (72.0)

216 (74.7)

0.42

 

yes

189 (28.0)

73 (25.3)

 

Calculus gallbladder(%)

no

524 (77.7)

227 (78.6)

0.85

 

yes

150 (22.3)

62 (21.4)

 

PE (%)

no

625 (92.7)

268 (92.7)

1

 

yes

49 (7.3)

21 (7.3)

 

Sepsis (%)

no

233 (34.6)

109 (37.7)

0.39

 

yes

441 (65.4)

180 (62.3)

 

MI (%)

no

605 (89.8)

263 (91.0)

0.64

 

yes

69 (10.2)

26 (9.0)

 

CHF (%)

no

549 (81.5)

231 (79.9)

0.64

 

yes

125 (18.5)

58 (20.1)

 

CVD (%)

no

632 (93.8)

266 (92.0)

0.40

 

yes

42 (6.2)

23 (8.0)

 

CPD (%)

no

528 (78.3)

217 (75.1)

0.31

 

yes

146 (21.7)

72 (25.9)

 

Diabetes (%)

no

450 (66.8)

197 (68.2)

0.73

 

yes

224 (33.2)

92 (31.8)

 

Renal disease (%)

no

566 (84.0)

233 (80.6)

0.24

 

yes

108 (16.0)

56 (19.4)

 

Severe liver disease (%)

no

591 (87.7)

257 (89.9)

0.66

 

yes

83 (12.3)

32 (11.1)

 

CCI

4.00 [2.00, 6.00]

4.00 [2.00, 7.00]

0.73

SOFA

4.00 [2.00, 7.00]

4.00 [2.00, 6.00]

0.82

GCS

15.00 [14.00, 15.00]

15.00 [14.00, 15.000]

0.31

SIRS

3.00 [2.00, 4.00]

3.00 [3.00, 4.00]

0.45

HR max (beats/min)

111.00 [94.25, 127.00]

110.00 [93.00, 125.00]

0.44

HR min (beats/min)

90.00 [75.00, 106.00]

89.00 [76.00, 103.00]

0.50

MBP max (mmHg)

96.00 [86.00, 111.00]

96.00 [84.00, 109.00]

0.31

MBP min (mmHg)

68.00 [57.00, 79.000]

68.00 [57.00, 82.00]

0.53

RR max (breaths/min)

27.00 [23.00, 32.000]

27.00 [22.50, 32.00]

0.89

RR min (breaths/min)

16.00 [13.13, 19.00]

16.00 [13.50, 19.00]

0.33

TEM max (℃)

37.06 [36.72, 37.56]

37.06 [36.72, 37.56]

0.75

TEM min (℃)

36.72 [36.44, 37.11]

36.72 [36.39, 37.11]

0.95

Lactate (mmol/L)

1.70 [1.30, 2.80]

1.70 [1.20, 2.80]

0.50

PH

7.37 [7.29, 7.43]

7.37 [7.30, 7.42]

0.62

PO2 (mmHg)

82.00 [52.00, 127.00]

82.00 [50.00, 138.00]

0.91

PCO2 (mmHg)

39.00 [33.00, 46.00]

39.00 [33.00, 46.00]

0.87

Hb min (g/dL)

10.60 [8.90, 12.20]

10.30 [8.60, 12.20]

0.26

MCV max (fl.)

93.00 [88.00, 98.00]

94.00 [89.00, 99.00]

0.15

PLT min(×109/L)

200.00 [133.25, 287.75]

185.00 [130.00, 282.00]

0.25

WBC max(×109/L)

13.80 [9.70, 19.60]

12.900 [9.20, 19.10]

0.36

MCH max (pg)

30.45 [28.93, 32.10]

30.90 [29.20, 33.10]

0.02

MCHC max (g/L)

33.03 (1.68)

33.19 (1.87)

0.19

RBC max (×1012/L)

3.66 [3.13, 4.28]

3.55 [3.06, 4.15]

0.08

RDW max

15.00 [13.90, 16.58]

15.00 [13.80, 16.80]

0.60

HCT

34.30 [29.50, 39.48]

33.60 [29.50, 38.20]

0.32

Aniongap

15.00 [13.00, 18.46]

15.00 [12.50, 18.50]

0.14

Bicarbonate (mmol/L)

22.00 [18.00, 25.00]

22.00 [19.00, 25.00]

0.59

BUN max (mg/dL)

23.00 [13.00, 39.00]

21.00 [13.00, 35.00]

0.56

Ca max (mg/dL)

8.20 [7.60, 8.80]

8.10 [7.60, 8.80]

0.53

Glucose max (mg/dL)

140.00 [110.00, 195.50]

138.00 [109.00, 198.00]

0.83

Na max (mmol/L)

139.00 [136.00, 142.00]

138.00 [135.00, 142.00]

0.04

K max (mmol/L)

4.20 [3.80, 4.70]

4.30 [3.80, 4.70]

0.54

Cl max (mmol/L)

105.00 [100.00, 110.00]

104.00 [100.00, 109.00]

0.31

Cr max (mg/dL)

1.10 [0.70, 1.90]

1.00 [0.70, 1.70]

0.42

Alb (g/dL)

2.80 [2.30, 3.30]

2.80 [2.40, 3.20]

0.67

INR max

1.30 [1.20, 1.60]

1.30 [1.20, 1.60]

0.79

PT max (s)

14.50 [13.20, 17.40]

14.40 [13.10, 17.90]

0.61

ALT max (U/L)

48.00 [24.00, 117.75]

41.00 [22.00, 106.00]

0.30

ALP max (U/L)

110.00 [71.00, 198.00]

109.00 [69.00, 190.00]

0.85

AST max (U/L)

71.00 [34.00, 188.00]

58.00 [31.00, 125.00]

0.02

Tbil max (mg/dL)

1.00 [0.60, 2.70]

0.90 [0.50, 3.00]

0.84

Ventilation (%)

no

619 (91.8)

269 (93.1)

0.60

 

yes

55 (8.2)

20 (6.9)

 

Vasopressin (%)

no

476 (70.6)

211 (73.0)

0.50

 

yes

198 (29.4)

78 (27.0)

 

Fluid Intake (ml/kg/d) (%)

< 50

262 (38.9)

136 (47.1)

0.02

 

>=50

412 (61.1)

153 (52.9)

UO (ml/kg/h) (%)

< 0.5

216(32.0)

82 (28.4)

0.29

 

>=0.5

458 (68.0)

207 (71.6)

Los hospital (days)

16.79 [7.94, 30.14]

13.09 [7.50, 23.76]

0.01

Los ICU (days)

3.58 [1.94, 9.25]

3.21 [1.86, 7.00]

0.12

AKI (%)

no

183 (27.2)

85 (29.4)

0.52

 

yes

491 (72.8)

204 (70.6)

  1. Abbreviations: AKI: Acute kidney injury, AP: Acute pancreatitis, PE: Pleural effusion, MI: Myocardial infarction, CHF: Chronic heart failure, CVD: Chronic cerebrovascular disease, CPD: Chronic pulmonary disease, CCI: Charlson comorbidity index, SOFA: Sequential organ failure assessment, GCS: Glasgow coma scale, SIRS: Systemic inflammatory response syndrome, HR: Heart rate, MBP: Mean blood pressure, RR: Respiratory rate, TEM: Temperature, HB: Hemoglobin, MCV: Mean corpuscular volume, PLT: Platelet count, WBC: White blood cell, MCH: Mean hemoglobin concentration, MCHC: Mean corpuscular hemoglobin content, RBC: Red blood cell, RDW: Red cell distribution width, HCT: Hematocrit, BUN: Blood urea nitrogen, ALB: Albumin, INR: International normalized ratio, PT: Prothrombin time, ALT: Alanine aminotransferase, ALP: Alkaline phosphatase, AST: Aspartate aminotransferase, TBIL: Total bilirubin, UO: Urine output, Los hospital: hospital length of stay, Los ICU: ICU length of stay
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