Table 3 Summary of study characteristics that reported the mean value of IL-6
First author, year (Reference) | N | Mean age, years, (SD) | Number of male (percentage) | Number of countries | Name of countries | Months on dialysis, Mean (SD) | Modality (HD or PD) | IL-6 (ng/ L) | ||
|---|---|---|---|---|---|---|---|---|---|---|
Type of blood | mean | SD | ||||||||
Istanbuly 2023 | 966 | 55.02 (15.25) | 560 (58.03) | 3 | the UK, Canada, Korea | 8.14 (15.94) | PD | plasma | 2.52 | 4.86 |
Lobo 2013 [48] | 45 | 54.6 (14.8) | 17 (37.7) | 1 | Brazil | 62.2 (51.4) | PD | plasma | 4.1 | 1.6 |
Wang 2017 [45] | 177 | 62.4 (14.05) | 112 (63.28) | 1 | China | 35.79 (33.70) | HD | plasma | 4.39 | 1.11 |
Liu 2017 [60] | 50 | 56 (14.24) | 21 (42) | 1 | Taiwan | Not reported | PD | plasma | 5.15 | 6.91 |
Lichtenberg 2015 [19] | 57 | 61.7 (15.9) | 31 (55) | 1 | Israel | 104.28 (71.52) | HD | serum | 5.43 | 2.61 |
Han 2009 [35] | 107 | 51.58 (11.2) | 49 (45.79) | 1 | Korea | 57.68 (19.3) | PD | serum | 8.58 | 7.4 |
Panichi 2011 [34] | 753 | 65.7 (14.2) | 457 (60.7) | 1 | Italy | Not reported | HD | serum | 8.7 | 14 |
Noori 2011 [41] | 799 | 54 (15) | 376 (47.05) | 1 | US | 28 (26) | HD | serum | 11.7 | 12.8 |
Bologa 1998 [61] | 90 | 62 | 39 (43) | 1 | US | 45.6 (not reported) | HD | plasma | 11.8 | Not reported |
Wetmore 2008 [54] | 236 | 62.7 (4.3) | 147 (62) | 1 | US | 64.8 (45.6) | HD | serum | 13 | 17.5 |
Rao 2005 [27] | 208 | 62.2 (12.5) | 94 (45.2) | 1 | US | 44.4 (51.6) | HD | plasma | 14.9 | 17.5 |
Kalantar-Zadeh 2006 [18] | 369 | 54.66 (14.39) | 195 (54.77) | 1 | US | 36.46 (33.81) | HD | serum | 23.2 | 57.97 |
Kato 2006 [62] | 154 | 59 (11) | 101 (65.58) | Not reported | Not reported | 13 (7) | HD | serum | 23.16 | 27.86 |
Kalantar-Zadeh 2004 [63] | 378 | 54.5 (14.7) | 201 (53.2) | 1 | US | 36.7 (33.9) | HD | serum | 22.6 | 56.57 |
Kimmel 1998 [52] | 230 | 54.4 (14.2) | 159 (69.1) | 1 | US | 33.7 (47.3) | HD | plasma | 92.3 | 117.9 |
Kimmel 2003 [49] | 240 | 55.1 (14.3) | 175 (72.9) | 1 | US | 49.5 (10.5) | HD | plasma | 92.9 | 117.6 |
Muzasti 2020 [42] | 106 | 53.85 (11.49) | 65 (61.3) | 1 | Indonesia | 69.43 (34.74) | HD | serum | 99.66 | 115.87 |
Summary mean from all studies, 4645 patients*, | 74.1 | 75.33 | ||||||||