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Table 4 Baseline hip geometric measurements and changes at 6 months in the placebo and zoledronic acid groups

From: The effect of zoledronic acid on hip geometry in renal transplant recipients: a double-blind placebo-controlled randomized study

 

Baseline

After 6 Months

Changes %

Parameter

zoledronic acid

placebo

P value

zoledronic acid

placebo

P value

zoledronic acid

placebo

P value

NN Subperiosteal diameter (cm) Width

3.527 (0.376)

3.693 (0.375)

0.233

3.578 (0.436)

3.557 (0.350)

0.889

1.409 (4.519)

-3.580 (4.387)

0.005

IT Subperiosteal diameter (cm) Width

5.608 (0.524)

5.769 (0.540)

0.412

5.614 (0.483)

5.736 (0.564)

0.522

0.248 (3.736)

-0.444 (5.594)

0.682

FS Subperiosteal diameter (cm) Width

3.211 (0.304)

3.166 (0.250)

0.672

3.211 (0.288)

3.213 (0.303)

0.990

0.093 (2.642)

1.420 (4.158)

0.286

NN endocortical diameter (cm)

3.201 (0.396)

3.402 (0.400)

0.175

3.237 (0.474)

3.252 (0.367)

0.925

1.0287 (5.329)

-4.260 (5.019)

0.009

IT endocortical diameter (cm)

4.881 (0.525)

5.084 (0.583)

0.318

4.868 (0.481)

5.066 (0.612)

0.320

-0.049 (4.570)

-0.241 (5.832)

0.919

FS endocortical diameter (cm)

2.128 (0.406)

2.171 (0.341)

0.760

2.073 (0.395)

2.200 (0.425)

0.400

-2.346 (7.611)

1.247 (8.723)

0.232

NN Cross-sectional area (cm2)

2.853 (0.487)

2.669 (0.358)

0.258

2.980 (0.519)

2.706 (0.377)

0.117

4.528 (5.880)

1.382 (4.937)

0.128

IT Cross-sectional area (cm2)

4.882 (0.800)

4.562 (0.681)

0.253

5.011 (0.821)

4.528 (0.663)

0.092

2.860 (6.173)

-0.298 (11.076)

0.319

FS Cross-sectional area (cm2)

4.483 (0.755)

4.130 (0.710)

0.199

4.667 (0.789)

4.237 (0.636)

0.117

4.385 (7.572)

3.118 (6.477)

0.630

NN CSMI (cm4)

2.928 (0.921)

2.812 (0.637)

0.699

3.079 (0.980)

2.741 (0.715)

0.300

5.651 (9.761)

-3.184 (8.222)

0.013

IT CSMI(cm4)

14.031 (4.450)

13.435 (3.900)

0.702

14.626 (4.655)

13.158 (3.947)

0.364

5.238 (13.763)

-0.202 (20.450)

0.382

FS CSMI(cm4)

4.363 (1.515)

3.875 (1.057)

0.327

4.415 (1.458)

3.953 (0.923)

0.324

1.821 (7.773)

3.298 (12.345)

0.686

NN Section modulus (cm3)

1.507 (0.385)

1.379 (0.221)

0.253

1.583 (0.408)

1.398 (0.273)

0.166

5.254 (7.567)

0.965 (8.197)

0.143

IT Section modulus (cm3)

4.197 (1.024)

3.969 (0.956)

0.535

4.436 (1.198)

3.952 (0.983)

0.243

5.840 (11.981)

0.401 (16.711)

0.299

FS Section modulus (cm3)

2.583 (0.649)

2.343 (0.486)

0.270

2.643 (0.636)

2.366 (0.433)

0.186

2.647 (5.850)

1.972 (11.894)

0.852

NN Cortical thickness (cm)

0.163 (0.027)

0.144 (0.023)

0.052

0.168 (0.033)

0.153 (0.023)

0.152

2.730 (8.149)

6.234 (5.888)

0.198

IT Cortical thickness (cm)

0.363 (0.054)

0.343 (0.050)

0.301

0.373 (0.058)

0.336 (0.058)

0.098

2.940 (6.903)

-1.666 (10.845)

0.159

FS Cortical thickness (cm)

0.540 (0.103)

0.499 (0.093)

0.286

0.568 (0112)

0.504 (0.092)

0.105

5.709 (10.434)

1.433 (8.738)

0.239

NN Buckling ratio

12.172 (3.071)

14.492 (3.385)

0.056

12.055 (4.118)

13.023 (2.462)

0.457

-2.088 (10.148)

-8.711 (11.500)

0.101

IT Buckling ratio

9.294 (1.749)

10.062 (1.968)

0.262

8.938 (1.670)

10.284 (2.690)

0.096

-3.502 (6.768)

1.595 (10.392)

0.108

FS Buckling ratio

3.189 (0.741)

3.423 (0.876)

0.428

3.000 (0.637)

3.469 (1.120)

0.149

-5.080 (11.120)

0.896 (12.879)

0.177

Neck Shaft Angle

126.06 (6.629)

127.08 (6.487)

0.672

124.444 (5.982)

125.538 (5.636)

0.611

-1.158 (4.397)

-1.128 (3.393)

0.983

  1. NN Narrow neck, IT Inter-trochanteric, FS Femoral shaft, CSMI Cross-sectional moment of inertia