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Table 2 Generalized estimating equations with robust variance estimator analysis for catheter dysfunction

From: Risk factors of hemodialysis catheter dysfunction in patients undergoing continuous renal replacement therapy: a retrospective study

 

Unadjusted OR (95% CI)

p-value

Adjusted OR (95% CI)

p-value

Age

1.02(1.00–1.04)

0.033

1.01(0.99–1.03)

0.163

Sex

1.09(0.67–1.78)

0.719

  

Weight

1.00(0.99–1.02)

0.853

  

Height

1.00(0.97–1.02)

0.707

  

Body mass index

1.01(0.96–1.06)

0.654

  

Hypertension

1.07(0.66–1.73)

0.788

  

Diabetes mellitus

1.11(0.69–1.78)

0.672

  

Dyslipidemia

1.21(0.75–1.96)

0.441

  

Atrial fibrillation

0.72(0.31–1.66)

0.440

  

Myocardial infarction

0.99(0.54–1.83)

0.979

  

Stroke

2.19(1.06–4.51)

0.035

1.97(0.93–4.13)

0.078

Chronic kidney disease

1.20(0.73–1.98)

0.461

  

Chronic hemodialysis

1.53(0.86–2.72)

0.146

  

History of any thrombosis event

0.70(0.29–1.72)

0.437

  

Medication of antiplatelet

0.84(0.45–1.57)

0.580

0.66(0.33–1.33)

0.248

Medication of anticoagulant

0.92(0.44–1.92)

0.834

1.02(0.55–1.92)

0.942

APACHE II score

1.01(0.98–1.04)

0.706

  

Catheterized vessel

 Right internal jugular vein

Reference

   

 Left internal jugular vein

0.92(0.44–1.92)

0.834

  

 Femoral vein

1.04(0.63–1.72)

0.866

  

Concurrent catheter in catheterized vessel

1.29(0.80–2.06)

0.295

1.80(0.95–3.39)

0.071

Concurrent catheter tip

1.01(0.62–1.64)

0.977

0.70(0.40–1.23)

0.828

Catheter tip location

 Superior vena cava

Reference

 

Reference

 

 Right atrium

0.28(0.08–0.94)

0.039

0.31(0.09–1.12)

0.074

 Left innominate vein

1.14(0.44–2.92)

0.790

1.32(0.46–3.74)

0.604

 Inferior vena cava

1.01(0.21–4.85)

0.990

1.36(0.25–7.35)

0.722

 Iliac vein

0.88(0.53–1.45)

0.604

1.02(0.56–1.86)

0.953

Mean blood flow

1.00(0.99–1.01)

0.440

1.00(0.99–1.00)

0.680

Circuit anticoagulation

1.26(0.76–2.10)

0.371

1.06(0.61–1.87)

0.828

Causes of CRRT

 End stage renal disease

Reference

   

 Sepsis

0.85(0.44–1.65)

0.627

  

 Nephrotoxic kidney injury

0.61(0.22–1.72)

0.350

  

 Ischemic kidney injury

0.85(0.44–1.61)

0.614

  

 Others

0.75(0.28–2.03)

0.577

  

Use of vasopressor

0.76(0.45–1.29)

0.311

  

Platelet count

1.00(1.00–1.00)

0.229

  

Prothrombin time

0.56(0.36–0.89)

0.013

0.49(0.30–0.82)

0.007

aPTT

1.00(0.99–1.01)

0.547

1.01(1.00–1.01)

0.049

hs-CRP level

0.99(0.97–1.02)

0.512

  
  1. Abbreviations: OR odds ratio, CI confidence interval, APACHE acute physiology and chronic health evaluation, CRRT continuous renal replacement therapy, aPTT activated partial thromoplastin time, hs-CRP high sensitivity C-reactive protein