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Table 1 Comparisons of demographic characteristics between participants with CKD stages 3, 4, and 5

From: Retinal changes and cardiac biomarker assessment in relation to chronic kidney disease: a single centre study

Demographic

All (n = 84)

CKD stage 3 (n = 28)

CKD stage 4 (n = 28)

CKD stage 5 (n = 28)

p-value

Gender

 Male

44 (52.4)

17 (38.6)

14 (31.8)

13 (29.5)

0.538a

 Female

40 (47.6)

11 (27.5)

14 (35)

15 (37.5)

Age

 Years

58.8 ± 11.7

55.21 ± 10.181

57.5 ± 11.462

57.75 ± 13.525

0.381b

Ethnicity

 Malay

64 (76.2)

23 (35.9)

21 (32.8)

20 (31.3)

0.0875a

 Chinese

16 (19.0)

4 (25)

6 (37.5)

6 (37.5)

 Indian

4 (4.8)

1 (25)

1 (25)

2 (50)

Cause of CKD

 DM

43 (51.2)

14 (32.6)

11 (25.6)

18 (41.9)

0.178a

 Hypertension

6 (7.1)

2 (33.3)

3 (50)

1 (16.7)

 IgAN

10 (11.9)

5 (50)

2 (20)

3 (30)

 FSGS

5 (6)

2 (40)

3 (60)

0 (0)

 Lupus nephritis

6 (7.1)

3 (50)

2 (33.3)

1 (16.7)

 Obstructive Uropathy

6 (7.1)

1 (16.7)

5 (83.3)

0 (0)

 Medullary Nephrocalcinosis

2 (2.4)

0 (0)

0 (0)

2 (100)

 Neurogenic Bladder

1 (1.2)

1 (100)

9 (0)

0 (0)

 VUR

1 (1.2)

0 (0)

1 (50)

0 (0)

 Single functioning Kidney post Nephrectomy

2 (2.4)

0 (0)

1 (50)

0 (0)

 ADPKD

1 (1.2)

0 (0)

0 (0)

1 (100)

 Unknown primary

1 (1.2)

0 (0)

0 (0)

1 (100)

Diabetes mellitus

54 (64.3)

18 (33.3)

15 (27.8)

21 (38.9)

0.247a

Hypertension

78 (92.9)

27 (34.6)

26 (33.3)

25 (32.1)

0.584a

IHD

20 (23.8)

6 (30)

7 (35)

7 (35)

0.936a

Stroke

13 (15.5)

5 (38.5)

3 (23.1)

5 (38.5)

0.695a

PVD

4 (4.8)

0 (0)

0 (0)

4 (100.0)

0.015a

Diabetic retinopathy

 Yes

18 (21.4)

5 (27.8)

4 (22.2)

9 (50)

0.194a

 No

36 (42.9)

13 (34.5)

11 (27.6)

12 (37.9)

 Not diabetic

30 (35.7)

10 (35.1)

13 (43.2)

7 (21.6)

Smoker

5 (6)

2 (40)

1 (20)

2 (40)

0.808a

Treatment

 ACEI

25 (29.8)

11 (44.0)

11 (44.0)

3 (12.0)

0.026a

 ARB

26 (30.9)

13 (50.0)

10 (38.5)

3 (11.5)

0.012a

 Beta blocker

32 (38.1)

11 (34.4)

9 (28.1)

12 (37.5)

0.702a

 CCB

57 (67.9)

18 (31.6)

17 (29.8)

22 (38.6)

0.318a

 Statin

69 (82.1)

24 (34.8)

22 (31.9)

23 (33.3)

0.903a

 Insulin

30 (35.7)

8 (26.7)

8 (26.7)

14 (46.7)

0.172a

  1. Abbreviations: Dmdiabetes mellitus, IgAN Immunoglobulin A nephropathy, FSGS Focal segmental glomerulosclerosis, VUR Vesicoureteral reflux, ADPKD Autosomal dominant polycystic kidney disease, IHD Ischaemic heart disease, PVD Peripheral vascular disease, ACEI Angiotensin converting enzyme inhibitors, ARB Angiotensin receptor blockers
  2. aChi-Square test
  3. bKruskal Wallis test