From: Diagnosing Fabry nephropathy: the challenge of multiple kidney disease
Blood pressure | Low levels in patients with normal kidney function, higher prevalence of hypertension with increasing age and in patients with CKD (mostly for GFR < 60 ml/min/1.73 m2) |
Kidney function | Hyperfiltration in early phasesb, then progressive decrease in GFR, up to CKD and ESKD |
Tubular manifestations | Distal renal tubular acidosis, isosthenuria, Fanconi syndrome, nephrogenic diabetes insipidus |
Urinalysis | Microalbuminuria in early phases, then clinically manifest proteinuria Nephrotic syndrome in adulthood (18% of untreated patients) Hematuria |
Urine Microscopy | Maltese crosses; Urinary mulberry cells; podocyturia |
Ultrasound | Renal cysts (mainly parapelvic) |