Scenario | Unit | Base case | Scenario | Result | Impact on results |
---|---|---|---|---|---|
Base case | - | - | - | -£25,460 | - |
OS HR (-2.5%) | - | 0.96 | 0.94 | -£7,047 | £18,413 |
Mean age-at-KF (30) | Years | 23.00 | 30.00 | -£43,221 | -£17,761 |
OS HR (+ 2.5%) | - | 0.96 | 0.99 | -£41,989 | -£16,529 |
Mean age-at-KF (18) | Years | 19.50 | 18.00 | -£9,551 | £15,910 |
Annual compliance score: 3 | ACS | 2.25 | 3.00 | -£37,950 | -£12,490 |
Number of transplants | - | 2.00 | 3.00 | -£18,261 | £7,200 |
Applying a HR of 1 to SKF curve in Poor Compliance | - | 1.01 | 1.00 | -£20,724 | £4,736 |
Graft failure time (17.50 years) | Years | 20.62 | 17.50 | -£29,114 | -£3,653 |
Waiting list for transplant time (36 months) | Months | 9.04 | 36.00 | -£28,856 | -£3,396 |
Discount rate (1.5%) | % | 0.04 | 0.02 | -£22,188 | £3,272 |
Graft failure time (22.50 years) | Years | 20.62 | 22.50 | -£23,500 | £1,961 |
Waiting list for transplant time (0 months) | Months | 9.04 | 0.00 | -£24,581 | £879 |