Table 1 General characteristics of the study participants
From: Cystatin C-derived estimated glomerular filtration rate in children with sickle cell anaemia
Variable | Subject (%) | Control (%) |
|---|---|---|
Age (years) | ||
1–5 | 30 (34.9) | 30 (34.9) |
6–10 | 38 (44.2) | 38 (44.2) |
>10 | 18 (20.9) | 18 (20.9) |
Sex | ||
Male | 40 (46.5) | 40 (46.5) |
Female | 46 (53.5) | 46 (53.5) |
Socioeconomic class | ||
Upper | 20 (23.2) | 64 (74.4) |
Middle | 30 (34.9) | 15 (17.5) |
Lower | 36 (41.9) | 7 (8.1) |
Age at sickle cell diagnosis | ||
<1 year | 11 (12.8) | --- |
1–5 year | 69 (80.2) | --- |
>5 year | 6 (7.0) | --- |
Routine medications | ||
Folic acid + Proguanil | 74 (86.0) | --- |
Folic acid + Proguanil + Hydroxyurea | 12 (14.0) | --- |
Steady-state PCV (%) | ||
<18 | 4 (4.7) | --- |
18–24 | 62 (72.1) | --- |
>24 | 20 (23.3) | --- |
Mean ± SD | 22.8 ± 2.8 | --- |
Frequency of crisis in the preceding year | ||
None | 3 (3.5) | --- |
1–2 | 71 (82.6) | --- |
≥3 | 12 (13.9) | --- |
Previous blood transfusion(s) | ||
Yes | 62 (72.1) | 7 (8.1) |
No | 24 (27.9) | 79 (91.9) |
Body mass index (BMI) classification | ||
Normal | 61 (70.9) | 63 (73.2) |
Thinness | 19 (22.1) | 4 (4.7) |
Severe thinness | 5 (5.8) | 0 (0.0) |
Overweight | 1 (1.2) | 17 (19.8) |
Obese | 0 (0.0) | 2 (2.3) |
Mean BMI (Kg/m2) | 16.3 ± 1.9 | 19.8 ± 1.3 |
Blood pressure (Mean ± SD) | ||
Systolic BP | 97.0 ± 9.0 | 103.4 ± 8.1 |
Diastolic BP | 57.8 ± 8.9 | 59.3 ± 7.0 |