Table 4 Relationship between some clinical findings and eGFR of the study subjects
From: Cystatin C-derived estimated glomerular filtration rate in children with sickle cell anaemia
Variable | eGFR (mL/min/1.73m2) | χ2 | df | p-value | |
|---|---|---|---|---|---|
≥ 90 | < 90 | ||||
Peripheral oedema | |||||
Present | 0 (0.0) | 2 (100.0) | |||
Absent | 67 (79.8) | 17 (20.2) | 5.662 | 1 | 0.017* |
Frequency of crisis | |||||
None | 3 (100.0) | 0 (0.0) | |||
1–2 | 55 (77.5) | 16 (22.5) | |||
≥3 | 9 (75.0) | 3 (25) | 0.255 | 2 | 0.993 |
Steady-state PCV | |||||
≤18 | 4 (100.0) | 0 (0.0) | |||
18–24 | 54 (79.4) | 14 (20.6) | |||
>24 | 9 (64.3) | 5 (35.7) | 1.849 | 2 | 0.763 |
Blood pressure | |||||
Low | 35 (76.1) | 11 (23.9) | |||
Normal | 29 (82.9) | 6 (17.1) | |||
Elevated BP | 3 (60.0) | 2 (40.0) | |||
Hypertension | 0 (0.0) | 0 (0.0) | 6.786 | 3 | 0.327 |
Routine medication | |||||
Folic acid + Proguanil | 57 (77.0) | 17 (23.0) | |||
Folic acid + Proguanil + Hydroxyurea | 11 (91.7) | 1 (8.3) | 1.337 | 1 | 0.248 |