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Table 1 Reported cases of renal CIC-rearranged sarcomas

From: Renal CIC-LEUTX rearranged sarcoma with multiple pulmonary metastases: a case report and literature review

Literature /Year

Age/Sex

Side/Size

IHC

CD99/WT1/ETV4

FISH

/Sequence

Status (month)

Mangray et al. /2016 [16]

9/Male

Right/10 cm

 + / + /U

CIC + ; EWSR1-;SYT-

/ CIC-DUX4

DOD (18)

Bergerat et al. /2017 [9]

29/Male

Right/15 cm

 + / + /U

CIC U; EWSR1-

/ CIC-DUX4a

DOD (5)

Camille et al. /2018 [10]

12/Male

Right/7.8 cm

 + / + /U

CIC-DUX4 + ; EWSR1-

/ CIC-DUX4

DOD (17)

Mangray et al. /2018 [15]

13/Female

Right/12.5 cm

 + / ± 

CIC-NUTM1 + 

/ CIC-NUTM1

NED (36)

Mangray et al. /2018 [15]

33/Female

Right/18 cm

 + / ± 

CIC + ; EWSR1-

/ U

DOC (6)

Mangray et al. /2018 [15]

82/Female

Left/5 cm

 + / + / + 

CIC + ; EWSR1-

/ CIC-DUX4

DOD (6)

Mangray et al. /2018 [15]

48/Female

Right/4.6 cm

 + / ± 

CIC U; EWSR1-;SYT-

/ CIC-DUX4

AWD (8)

This case

45/Male

Left/12.2 cm

 + / ± 

CIC + 

/ CIC-LEUTX

DOC (7)

  1. Abbreviations: AWD alive with disease, DOC died of complications, DOD died of disease, NED no evidence of disease, U unknown
  2. aRT-PCR results