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Table 1 The characteristic of included studies

From: Objectively measured daily steps as an outcome in a clinical trial of chronic kidney disease: a systematic review

First author [Ref.]

Year

Study design

Subjects (n)

Age (y)

Population

Intervention type

Duration

Physical activity measurement

Outcome

Exercise training-based interventions

Masajtis-Zagajewska A et al. [19]

2019

Single-arm trial

39

46.9 ± 11.8

KTR (n = 24) and stage 3–4 CKD (n = 15)

Structured Physical Activity Program

12 weeks

3-axis SenseWear MF Armband accelerometer

Primary outcome

Assawasaksakul, N et al. [17]

2021

RCT

I: 6

C: 6

I:52.5 ± 12.9

C: 53.7 ± 17.2

HD

Intradialytic cycling exercise VS. usual care

24 weeks

Wrist-worn triaxial accelerometer

Primary outcome

Martins do Valle F et al. [18]

2020

RCT

I: 12

C: 12

I: 49.3 ± 12.4

C: 60.4 ± 10.6

HD

Intradialytic resistance exercise VS. usual care

12 weeks

Triaxial accelerometer

Primary outcome

Young HML et al. [24]

2020

RCT

I: 24

C: 27

I: 59 ± 13

C: 65 ± 11

HD

Intradialytic cycling exercise VS. usual care

24 weeks

SenseWear Armband Pro 3

Secondary outcome

Watanabe K et al. [23]

2021

RCT

I: 26

C: 27

I: 66.19 ± 13.05

C: 64.00 ± 12.95

PD

Intradialytic combination exercise VS. usual care

24 weeks

Three-axis accelerometer

Secondary outcome

Otobe Y et al. [30]

2021

RCT

I: 27

C: 26

I: 78.4 ± 6.4

C: 78.1 ± 7.4

Stage 3–4 CKD

Exercise training VS. usual care

24 weeks

Kenz Lifecorder Ex 1 axial accelerometer

Secondary outcome

Graham-Brown MPM et al. [26]

2021

RCT

I: 65

C: 65

I: 55.5 ± 15.5

C: 58.9 ± 14.9

HD

Intradialytic cycling exercise VS. usual care

24 weeks

Triaxial accelerometers

Secondary outcome

Hiraki K et al. [27]

2017

RCT

I: 14

C: 14

I: 69.0 ± 6.8

C: 67.8 ± 6.9

Stage 3–4 CKD

Home-based exercise program VS. usual care

84 weeks

Pedometers

Secondary outcome

Kontos P et al. [28]

2020

Quasi-experiment study

I: 10

C: 9

I: 72.7 ± 7.9

C: 73.9 ± 5.4

HD

Viewed Fit for Dialysis before participating in a 16-week exercise VS. usual care

16 weeks

Pedometers

Primary outcome

Bulckaen M et al. [25]

2011

Quasi-experiment study

18

N.P.

HD

Advised walking VS. supervised walking

6 months

Pedometers

Primary outcome

Daily step goal-oriented interventions

Sheshadri A et al. [22]

2020

RCT

I: 30

C: 30

I: 56 [51–65]

C: 60 [53–66]

Dialysis

Pedometers with weekly step goals VS. usual care

6 months

Pedometers

Primary outcome

Nowicki M et al. [29]

2010

Single-arm trial

33

58.3 ± 10.1

HD

Pedometers with weekly step goals

16 weeks

Pedometers

Primary outcome

O’Brien T et al. [20]

2020

RCT

I: 72

C: 26

I: 65.7 ± 4.9

C: 65.1 ± 4.0

KTR

SystemCHANGETM (Change Habits by Applying New Goals and Experience) + Activity Tracker intervention VS. attention

6 months

Number of daily steps recorded by Fitbit Charge 2

Secondary outcome

Malhotra R et al. (2023) [33]

2023

RCT

I: 28

C: 27

I: 62 ± 13

C: 61 ± 14

HD

Fitbit + feedback VS. Fitbit

12 weeks

Activity tracker

Primary outcome

Mobile health (mHealth) interventions

Anand S et al. (2021) [31]

2021

RCT

I: 28

C: 28

I: 56.2 ± 12.3

C: 58.1 ± 9.9

Stage 3b-4 CKD

mHealth + exercise training VS. exercise training

16 weeks

Activity tracker

Secondary outcome

Different dialysis modalities

Pecoits-Filho R et al. [21]

2021

RCT

HDF: 97

HD: 98

HDF: 52.6 ± 15.9

HD: 53.3 ± 14.3

HD

Hemodiafiltration VS. high-flux HD

6 months

Triaxial accelerometer

Primary outcome

Sit Less, Interact, Move More intervention

Lyden K et al. [32]

2021

RCT

I: 54

C: 52

I: 69 ± 14

C: 69 ± 12

Stage 2–5 CKD

Sit Less, Interact, Move More VS. standard care

24 weeks

activPAL accelerometer

Primary outcome

  1. Abbreviations: I, intervention; C, control; AE, aerobic exercise; RT, resistance training; CE, combined exercise; CKD, chronic kidney disease; HD, hemodialysis; KTR, kidney transplant recipient; HDF, hemodiafiltration; RCT, randomized control trial; N.P, not report
  2. Median [quartiles]