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Fig. 2 | BMC Nephrology

Fig. 2

From: IL-33/ST2L signaling alleviates diabetic nephropathy by regulating endoplasmic reticulum stress and apoptosis

Fig. 2

The expression of IL-33 and sST2 in DN. (A) Identification of IL-33 and sST2 from GEO datasets (GSE96804) in heath control (HC; n = 19) and DN patients (n = 42). (B) Quantitative real-time PCR analysis of IL-33 and sST2 in STZ-induced mice (n = 6 each). The expression level in the Control group was assigned a value of 1. Data are expressed as means ± SEM. **p < 0.01. (C) Double immunostaining with anti-CD31 and anti-IL-33 in kidney sections. Scale bars = 50 μm. Fluorescence colocalization ratio analysis showed that the expression of IL33 in glomeruli was significantly increased in STZ mice

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BMC Nephrology

ISSN: 1471-2369

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