From: Association between serum lipoprotein(a) and mildly reduced eGFR: a cross-sectional study
Variables | Lipoprotein(a) tertiles | P for trend | ||
---|---|---|---|---|
Tertile 1 | Tertile 2 | Tertile 3 | ||
Numbers(n,%) | 354 (32.27) | 354 (33.27) | 356 (33.46) | - |
Lipoprotein(a)(mg/L) | 26.0 (19.0–35.0) | 77.5 (60.0–99.0) | 186.0 (133.5-261.9) | < 0.0001 |
Age (years) | 67.5 ± 8.1 | 65.9 ± 8.0 | 67.1 ± 9.2 | 0.54 |
Male (n,%) | 120 (33.9) | 130 (36.7) | 120 (33.7) | 0.96 |
BMI (kg/m2) | 25.5 ± 3.6 | 25.9 ± 3.2 | 24.8 ± 3.5 | 0.009 |
Current smoker (n,%) | 45 (12.82) | 52 (14.73) | 44 (12.39) | 0.87 |
Current drinker (n,%) | 13 (3.70) | 29 (8.26) | 17 (4.80) | 0.53 |
High physical activity (n,%) | 217 (61.3) | 200 (56.5) | 220 (61.8) | 0.89 |
SBP(mmHg) | 133.0 ± 13.9 | 134.0 ± 14.4 | 134.6 ± 15.3 | 0.15 |
DBP(mmHg) | 82.3 ± 7.9 | 83.9 ± 9.0 | 82.6 ± 8.8 | 0.59 |
ALT (U/L) | 20 (15–27) | 19 (15–27) | 18 (14–25) | 0.02 |
AST (U/L) | 23 (20–28) | 22 (19–27) | 22 (19–26) | 0.04 |
TG (mmol/L) | 1.79 (1.34–2.50) | 1.61 (1.21–2.18) | 1.42 (1.10–1.96) | < 0.0001 |
TC (mmol/L) | 5.07 ± 0.98 | 5.09 ± 1.01 | 5.18 ± 0.96 | 0.14 |
HDL-c (mmol/L) | 1.30 ± 0.29 | 1.33 ± 0.29 | 1.39 ± 0.31 | < 0.0001 |
LDL-c (mmol/L) | 2.69 ± 0.68 | 2.67 ± 0.69 | 2.76 ± 0.68 | 0.17 |
UA (µmol/L) | 303.3 ± 69.6 | 301.8 ± 71.2 | 299.6 ± 72.0 | 0.49 |
FPG (mmol/L) | 5.57 (4.69–6.73) | 5.50 (4.86–6.87) | 5.49 (4.79–6.72) | 0.74 |
Scr (µmol/L) | 73.21 ± 13.04 | 71.96 ± 12.08 | 73.22 ± 12.01 | 0.99 |
Scys (mg/L) | 0.78 ± 0.14 | 0.83 ± 0.14 | 0.83 ± 0.15 | < 0.0001 |
eGFR (mL/min/1.73m2) | 90.14 ± 13.48 | 89.06 ± 13.51 | 87.30 ± 14.02 | 0.006 |
Hypertension (n, %) | 242 (69.34) | 222 (63.43) | 241 (68.08) | 0.73 |
Diabetes (n, %) | 146 (41.95) | 120 (34.19) | 130 (37.14) | 0.19 |