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Table 1 Characteristics according to Lipoprotein(a) tertiles

From: Association between serum lipoprotein(a) and mildly reduced eGFR: a cross-sectional study

Variables

Lipoprotein(a) tertiles

P for trend

Tertile 1

Tertile 2

Tertile 3

Numbers(n,%)

354 (32.27)

354 (33.27)

356 (33.46)

-

Lipoprotein(a)(mg/L)

26.0 (19.0–35.0)

77.5 (60.0–99.0)

186.0 (133.5-261.9)

< 0.0001

Age (years)

67.5 ± 8.1

65.9 ± 8.0

67.1 ± 9.2

0.54

Male (n,%)

120 (33.9)

130 (36.7)

120 (33.7)

0.96

BMI (kg/m2)

25.5 ± 3.6

25.9 ± 3.2

24.8 ± 3.5

0.009

Current smoker (n,%)

45 (12.82)

52 (14.73)

44 (12.39)

0.87

Current drinker (n,%)

13 (3.70)

29 (8.26)

17 (4.80)

0.53

High physical activity (n,%)

217 (61.3)

200 (56.5)

220 (61.8)

0.89

SBP(mmHg)

133.0 ± 13.9

134.0 ± 14.4

134.6 ± 15.3

0.15

DBP(mmHg)

82.3 ± 7.9

83.9 ± 9.0

82.6 ± 8.8

0.59

ALT (U/L)

20 (15–27)

19 (15–27)

18 (14–25)

0.02

AST (U/L)

23 (20–28)

22 (19–27)

22 (19–26)

0.04

TG (mmol/L)

1.79 (1.34–2.50)

1.61 (1.21–2.18)

1.42 (1.10–1.96)

< 0.0001

TC (mmol/L)

5.07 ± 0.98

5.09 ± 1.01

5.18 ± 0.96

0.14

HDL-c (mmol/L)

1.30 ± 0.29

1.33 ± 0.29

1.39 ± 0.31

< 0.0001

LDL-c (mmol/L)

2.69 ± 0.68

2.67 ± 0.69

2.76 ± 0.68

0.17

UA (µmol/L)

303.3 ± 69.6

301.8 ± 71.2

299.6 ± 72.0

0.49

FPG (mmol/L)

5.57 (4.69–6.73)

5.50 (4.86–6.87)

5.49 (4.79–6.72)

0.74

Scr (µmol/L)

73.21 ± 13.04

71.96 ± 12.08

73.22 ± 12.01

0.99

Scys (mg/L)

0.78 ± 0.14

0.83 ± 0.14

0.83 ± 0.15

< 0.0001

eGFR (mL/min/1.73m2)

90.14 ± 13.48

89.06 ± 13.51

87.30 ± 14.02

0.006

Hypertension (n, %)

242 (69.34)

222 (63.43)

241 (68.08)

0.73

Diabetes (n, %)

146 (41.95)

120 (34.19)

130 (37.14)

0.19

  1. Data were means ± SD for normal variables, medians (interquartile ranges) for skewed variables, and numbers (percentages) for categorical variables
  2. P values for trend were calculated by using linear regression analyses and Cochran-Armitage trend test for continuous and categorical variables across the three groups, respectively
  3. Abbreviations: BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, ALT Alanine aminotransferase, AST Aspartate aminotransferase, TC Total cholesterol, TG Triglycerides, HDL-c High-density lipoprotein cholesterol, LDL-c Low-density lipoprotein cholesterol, UA Uric acid, FPG Fasting plasma glucose, Scr Serum creatinine, Scys Serum cystatin C, eGFR Estimated glomerular filtration rate