- Mild represent the group of patients whose fraction of FN lesions is less than 1/16; Moderate represent the group of patients whose fraction of FN lesions is among 1/16 to 1/10; Severe represent the group of patients whose fraction of FN lesions is over 1/10, MAP mean arterial pressure, Scr serum creatinine, eGFR estimated glomerular filtration rate, UA serum uric acid, MEST-C MEST-C scores by Oxford classification; ESRD, end stage renal disease, defined by eGFR < 15 ml/min/1.73 m^2; Composite endpoint, defined by either a ≥ 30% reduction in eGFR, a doubling of the base-line serum creatinine, ESRD, chronic dialysis for at least 6 months or renal transplantation, RASB renin-angiotensin system blocker, IS immunosuppressive agents
