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Table 4 Macronutrients, Fatty acids, and micronutrients outcomes assessment with 24-h dietary records

From: Effects of a low-protein nutritional formula with dietary counseling in older adults with chronic kidney disease stages 3–5: a randomized controlled trial

 

Intervention group (n = 24)

Control group (n = 23)

 P-valueb

Baseline

3 months

Change in value

(3 months-Baseline)a

Baseline

3 months

Change in value

(3 months-Baseline)a

Macronutrients

 Energy (kcal)

1567 (1288–1837)

1632 (1472–1852)

137 (-67–200)

1521 (1284–1704)

1512 (1273–1700)

6 (-175–175)

0.20

 Energy

(kcal/kg body weight)

26.0 (22.1–35.0)

29.4 (23.3–34.7)

1.8 (-1.6–4.4)

23.2 (18.6–27.4)

22.5 (20.7–26.1)

0.1 (-2.8–2.4)

0.19

 Protein intake (g)

52.5 (36.8–68.7)

50.5 (42.8–56.6)

-3.7 (-14.7–5.3)

46.7 (41.6–55.6)

48.2 (43.7–52.9)

2.1 (-7.4–9.9)

0.37

 Protein intake

(g/kg body weight)

0.88 (0.66–1.21)

0.85 (0.65–1.05)

-0.07 (-0.23–0.09)

0.73 (0.55–0.93)

0.75 (0.62–0.86)

0.05 (-0.15–0.14)

0.41

 Carbohydrate intake (g)

213 (184–249)

222 (179–257)

12 (-17–38)

194 (165–239)

213 (168–241)

2 (-36–41)

0.87

 Fat intake (g)

61 (46–70)

68 (54–74)

6 (-5–23)

51 (43–70)

50 (45–66)

-1 (-11–9)

0.08

 Dietary fiber (g)

11.4 (8.6–15.1)

12.2 (7.6–11.8)

2.1 (-3.3–4.7)

12.5 (7.1–15.1)

10.6 (9.3–15.6)

-0.6 (-4.6–3.4)

0.36

Fatty acids composition

 SFA (g)

15.9 (10.2–18.2)

16.7 (13.6–21.2)

4.0 (-2.5–8.1)

11.9 (9.2–16.1)

12.8 (9.3–16.3)

-0.3 (-4.2–3.1)

0.17

 PUFA (g)

19.1 (15.7–25.7)

23.6 (16.1–26.5)

1.8 (-3.9–8.5)

22.4 (17.1–32.3)

20.8 (16.4–23.0)

-2.1 (-12.2–3.1)

0.09

 MUFA (g)

17.6 (11.9–21.0)

24.8 (20.0–27.8)

7.9 (2.5–11.7)§

13.1 (10.8–21.1)

12.9 (10.5–18.4)

-0.9 (-5.3–1.2)

 < 0.001**

 EPA (mg)

17.9 (4.5–60.9)

109.4 (86.7–130.3)

83.0 (47.0–105.9)§

4.5 (1.0–86.6)

4.6 (1.4–12.6)

-0.4 (-81.9–3.6)

 < 0.001**

 DHA (mg)

88.4 (46.7–160.4)

119.8 (106.3–209.4)

48.7 (-74.9–145.3)

62.1 (34.4–372.6)

41.9 (27.8–73.7)

-20.4 (-149.4–1.6)§

0.009**

Micronutrients

 Sodium (mg)

1138 (470–1966)

1132 (454–1615)

19 (-759–451)

1121 (668–1807)

1258 (656–1831)

15 (-554–601)

0.70

 Potassium (mg)

1463 (1004–2017)

1403 (934–2335)

89 (-522–668)

1336 (963–1972)

1346 (1024–2087)

170 (-521–589)

0.88

 Calcium (mg)

206 (156–299)

447 (319–759)

198 (113–384)§

421 (225–564)

392 (249–588)

-47 (-332–317)

0.014*

 Magnesium (mg)

143 (106–202)

152 (129–218)

33 (-50–80)

133 (110–208)

149 (107–201)

12 (-34–69)

0.88

 Phosphorus (mg)

593 (466–777)

647 (499–732)

-4 (-165–189)

595 (498–769)

592 (490–773)

54 (-295–109)

0.57

 Iron (mg)

6.0 (4.7–8.8)

10.1 (8–13.7)

4.3 (2.0–6.3)§

6.5 (4.6–10.4)

6.9 (3.2–9.8)

-1.2 (-2.5–1.8)

 < 0.001**

 Zinc (mg)

6.8 (5.0–8.2)

9.0 (8.3–9.6)

2.3 (0.6–3.4)§

5.9 (4.9–7.4)

6.2 (5.5–6.7)

0.0 (-1.2–1.3)

0.001**

 Copper (μg)

42.9 (10.6–65.2)

423.5 (409.2–447.4)

397.1 (356.0–415.1)§

39.3 (4.2–56.4)

13.6 (5.8–41.5)

-5.1 (-31.7–8.8)

 < 0.001**

 Vitamin E α-T.E (mg)

27.0 (16.9–34.6)

31.8 (20.3–36.8)

5.2 (-6.5–15.5)

31.6 (21.6–40.2)

26.9 (22.8–29.6)

-0.1 (-10.9–7.8)

0.11

 Vitamin C (mg)

68 (53–149)

91 (57–195)

24 (-35–114)

101 (43–166)

108 (63–215)

-13 (-71–109)

0.54

 Thiamine (mg)

0.8 (0.6–0.9)

1.2 (1–1.3)

0.4 (0.2–0.6)§

0.8 (0.5–1.1)

0.8 (0.6–1.2)

0.1 (-0.3–0.5)

0.037*

 Riboflavin (mg)

0.7 (0.5–1.2)

1.3 (1.1–1.5)

0.5 (0.2–0.8)§

0.9 (0.5–1.2)

0.8 (0.5–1.2)

0.1 (-0.3–0.3)

 < 0.011**

 Niacin (mg NE)

8.0 (5.6–11.3)

15.7 (13.2–17.1)

7.5 (3.3–9.7)§

8.5 (5.1–12.1)

8.1 (5.5–12.6)

0.3 (-4.5–2.8)

 < 0.001**

 Vitamin B6 (mg)

1.0 (0.9–1.4)

2.3 (2–2.6)

1.2 (0.9–1.4)§

0.9 (0.7–1.5)

1.0 (0.8–1.3)

0.0 (-0.1–0.2)

 < 0.001**

 Vitamin B12 (μg)

1.8 (1.2–2.3)

2.7 (2.2–3.7)

1.1 (0.2–2.1)§

1.2 (0.8–2.4)

1.5 (0.6–1.8)

-0.4 (-1.6–0.9)

0.006**

 Folate (μg)

150 (91–221)

313 (267–373)

162 (75–233)§

125 (89–177)

107 (76–165)

-9 (-70–75)

 < 0.001**

  1. Data are expressed as the median (interquartile range)
  2. SFA saturated fatty acids, PUFA polyunsaturated fatty acids, MUFA monounsaturated fatty acids, EPA eicosapentaenoic acid, DHA docosahexaenoic acid
  3. aGroups from baseline to 3 months were compared through the Wilcoxon signed-rank test (§P < 0.01)
  4. bValue change differences between the two groups as determined by the Mann–Whitney U test (*P < 0.05 and ** P < 0.01)