Fig. 7From: Adenine model of chronic renal failure in rats to determine whether MCC950, an NLRP3 inflammasome inhibitor, is a renopreventiveRepresentative micrograph of the kidney of the studied group stained with H&E. A Control negative group showing normal architecture of the Kidney. B, C Adenine induced CRF group showing vacuolar degeneration of the renal tubule, focal area of mononuclear cell infiltration and loss of architecture of the glomeruli with destruction of the Bowman's capsule. D MCC950 treated group showed improvement of the tubular cells with recovery of the architecture of the glomeruliBack to article page