Adenine model of chronic renal failure in rats to determine whether MCC950, an NLRP3 inflammasome inhibitor, is a renopreventive

Table 2 Effects of MCC950 treatment in adenine-induced chronic renal failure (CRF) on the percentage expression of interleukin-1 beta (IL-1β) and caspase-3 in the kidney of rats

Group Immune stain	Control -ve	Adenine-induced CRF group	MCC950 treated group
IL-1beta	14.52^a	49.75^b	22.74^a
Caspase-3	11.05^a	44.06^b	18.50^a

^a,^b values are not sharing a common superscript letter differ significantly at P < 0.05

ISSN: 1471-2369