Table 1 Baseline characteristics of BioMedioR participants by PENK-A quartiles^a, weighted

PENK-A range, pmol/L

< 49

49–59

60–74

> 74

Sample size, unweighted

1032

988

996

899

Weighted N

1958

1958

1957

1957

Age, years (SD)

62 (7)

63 (8)

65 (8)

67 (8)

Female, n (%)

803 (41)

920 (47)

939 (48)

1134 (58)

Black, n (%)

1234 (63)

1116 (57)

900 (46)

861 (44)

Body mass index, kg/m² (SD)

32 (6)

31 (6)

29 (5)

28 (5)

Diabetes mellitus, n (%)

705 (36)

627 (32)

430 (22)

528 (27)

Cardiovascular disease, n (%)

313 (16)

352 (18)

274 (14)

372 (19)

Systolic blood pressure, n (SD)

131 (16)

128 (16)

130 (17)

128 (17)

Diastolic blood pressure, n (SD)

79 (9)

78 (9)

77 (10)

75 (9)

Current tobacco use, n (%)

274 (14)

196 (10)

235 (12)

156 (8)

Serum creatinine, mg/dL (IQR)

0.79 (0.70, 0.92)

0.80 (0.70, 0.98)

0.89 (0.73, 0.98)

0.98 (0.79, 1.17)

Median serum cystatin C, mg/dL (IQR)

0.86 (0.76, 0.98)

0.89 (0.82, 1.03)

0.95 (0.85, 1.05)

1.09 (0.96, 1.31)

Median eGFR, ml/min/1.73m2 (IQR)^b

98 (86, 107)

92 (81, 100)

87 (77, 96)

71 (56, 83)

Median uACR, mg/g (IQR)

8 (5, 22)

8 (4, 17)

7 (4, 15)

9 (5, 32)