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Table 1 Characteristics of included studies

From: Mortality and mode of dialysis: meta-analysis and systematic review

Author (Year)

Design

Inclusion criteria

n (% male)

Mean/median age

Duration

Mortality

Continuous Renal Replacement Therapy (CRRT) versus Peritoneal Dialysis (PD)

 Al-Hwiesh et al. [27]

(2018)

RCT

• AKI requiring KRT

CRRT = 62 (72.6%)

PD = 63 (74.6%)

CRRT = 44.6 ± 12.4

PD = 45.4 ± 4.1

28 days

CRRT = 53.2%

PD = 30.2%

 George et al. [28]

(2011)

RCT

• AKI

• No history of abdominal surgery

• No pulmonary edema

CRRT = 25 (60%)

PD = 25 (64%)

CRRT = 45.3 ± 17.5

PD = 45.3 ± 17.5

3 years

CRRT = 84%

PD = 72%

 Jaryal et al. [29]

(2017)

R-Obs

• > 12 years

• GFR < 60 ml/min/1.73m2

CRRT = 22 (50%)

PD = 18 (66.7%)

CRRT = 55.5 ± 19

PD = 51.1 ± 16

1 year

CRRT = 81.8%

PD = 77.8%

 Phu et al. [30]

(2002)

RCT

• > 15 years

• AKI requiring KRT

CRRT = 34 (88%)

PD = 36 (75%)

CRRT = 35 (29.5–38.2)

PD = 36 (29.6–38.4)

1 year

CRRT = 15%

PD = 47%

Peritoneal Dialysis (PD) versus Hemodialysis (HD)

 Basu et al. [31]

(2016)

R-Obs

• 1 month to 16 years

• Uremia, oliguria, anuria, and severe metabolic acidosis

• Non-responsive fluid overload,

• Persistent hyponatremia

PD = 84 (51%)

HD = 52 (67%)

PD = 3.2 (0.1–7.6)

HD = 8.4 (3.2–15.6)

30 days

PD = 39.3%

HD = 66.3%

 Fenton et al. [32]

(1997)

R-Obs

• ESRD

• No history of dialysis or kidney transplant

PD = 2841 (NR)

HD = 7792 (NR)

NR

5 years

PD = 26.2%

HD = 30.9%

 Gabriel et al. [33]

(2008)

RCT

• With acute tubular necrosis

PD = 60 (72%)

HD = 60 (66%)

PD = 62.5 ± 21.2

HD = 64.2 ± 19.8

60 days

PD = 58%

HD = 53%

 Murphy et al. [34]

(2000)

P-Obs

• Patients with renal failure of any kind

PD = 282 (59.9%)

HD = 540 (58.7%)

PD = 56.1 (54.2–58.0)

HD = 59.4 (58.1–60.7)

6 months

PD = 33.8%

HD = 39.8%

 He et al. [35]

(2020)

R-Obs

• Patient with ESRD

PD = 501 (58%)

HD = 436 (53.9%)

PD = 51.69 ± 14.47

HD = 57.11 ± 15.92

5 years

PD = 4%

HD = 21%

 Liem et al. [36]

(2007)

R-Obs

• > 18 years

• Requiring > 30 days KRT

PD = 5802 (61.3%)

HD = 10,841 (57.5%)

PD = 53.6 ± 15

HD = 61.8 ± 14.6

6 months

Hazard ratio (PD vs. HD) = 0.70 (95% CI 0.67–0.74)

Hemodialysis (HD) versus Continuous Renal Replacement Therapy (CRRT)

 Gaudry et al. [15]

(2022)

RCT

• AKI requiring KRT

HD = 274 (63.9%)

CRRT = 269 (62.4%)

HD = 66.8 ± 13.3

CRRT = 66.2 ± 13.4

60 days

HD = 46.3%

CRRT = 54.3%

 Liang et al. [37]

(2016)

R-Obs

• No history of chronic kidney dialysis, transplant, or heart failure

• Creatinine level < 4 mg/dl

HD = 353 (57.5%)

CRRT = 285 (58.6%)

NR

90 days

HD = 55.9%

CRRT = 60%

 Schefold et al. [38]

(2014)

RCT

• > 18 years

• AFR requiring KRT

HD = 128 (63.3%)

CRRT = 122 (61.5%)

HD = 60.8 ± 13.4

CRRT = 62.3 ± 14.5

30 days

HD = 52.4%

CRRT = 45.4%

 Truche et al. [39]

(2016)

P-Obs

• Patients who received MV for ≥ 48 h in an ICU setting

• No history of kidney transplant, CKD requiring KRT, or heart disease

HD = 816 (65%)

CRRT = 544 (63.6%)

HD = 66.4 (54.8–76.1)

CCRT = 64.3 (52.4–74.3)

30 days

CRRT = 46.5%

HD = 35%

 Yilmaz Aydin et al. [40]

(2022)

P-Obs

• AKI requiring KRT

• No history of CKD or ESRD

HD = 80 (38.7%)

CRRT = 40 (37.5%)

HD = 61.4 ± 15.2

CRRT = 65.9 ± 9.1

30 days

HD = 66.3%

CRRT = 67.5%

  1. AKI  acute kidney injury, ARF Acute renal failure, ESRD end-stage renal disease, GFR glomerular filtration rate, KRT  renal replacement therapy, MV mechanical ventilation, NR  not reported, P-Obs  prospective observational study, R-Obs retrospective observational study