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Table 5 Univariate and multivariate logistic regression of the factors associated with DRPs among patients with kidney dysfunction at MRRH

From: Drug-related problems and associated factors among patients with kidney dysfunction at a tertiary hospital in southwestern Uganda: a prospective observational study

Variables

Category

DRP

COR (95% CI)

P value

AOR (95% CI)

P value

No

Yes

Gender

Male

22 (20.2)

87 (79.8)

1.09 (0.51–2.31)

0.831

  

Female

14 (21.5)

51 (78.5)

1

   

Age group

< 50

20

68

1

   

>=50

16

70

1.29 (0.62–2.69)

0.503

  

Employment status *

Worker

25 (18.1)

113 (81.9)

3.01 (0.79–11.48)

0.106

4.43 (0.70-27.95)

0.113

Employee

7 (26.9)

19 (73.1)

1.81 (0.39–8.39)

0.448

7.61 (0.85–68.14)

0.07

Self-employed

4 (40)

6 (60)

1

   

Smoking history

No

32 (21.8)

115 (78.2)

1

   

Yes

4 (14.8)

23 (85.2)

1.6 (0.52–4.96)

0.416

  

Alcohol history *

No

23 (24.2)

72 (75.8)

1

   

Yes

13 (16.5)

66 (83.5)

1.62 (0.76–3.46)

0.211

1.99 (0.81–4.91)

0.136

Patients able to afford prescribed medicine*

No

1 (4.8)

20 (95.2)

5.93 (0.77–45.78)

0.088

2.0 (0.23–17.58)

0.534

Yes

35 (22.9)

118 (77.1)

1

   

Medicine use without a prescription

No

30 (20.5)

116 (79.5)

1.06 (0.39–2.83)

0.916

  

Yes

6 (21.4)

22 (78.6)

1

   

Herbal medicine use

No

34 (21.5)

124 (78.5)

1

   

Yes

2 (12.5)

14 (87.5)

1.92 (0.42–8.86)

0.403

  

Number of comorbidities

None

9 (25.0)

27 (75.0)

1

   

One

20 (21.1)

75 (78.9)

1.25 (0.51–3.08)

0.628

  

Two or more

7 (16.3)

36 (83.7)

1.71 (0.57–5.18)

0.34

  

Type of kidney disease

AKI

19 (20.9)

72 (79.1)

0.747 (0.36–1.56)

0.436

  

CKD

17 (20.5)

66 (79.5)

1

   

Polypharmacy

No

4 (21.1)

15 (78.9)

1

   

Yes

32 (20.6)

123 (79.4)

1.03 (0.32–3.30)

0.967

  

Hypertension

No

22 (23.7)

71 (76.3)

1

   

Yes

14 (17.3)

67 (82.7)

1.48 (0.70–3.14)

0.302

  

HIV*

No

26 (18.6)

114 (81.4)

1.83 (0.78–4.28)

0.166

1.6 (0.57–4.51)

0.386

Yes

10 (29.4)

24 (70.6)

1

   

Anaemia

No

8 (18.2)

36 (81.8)

1.33 (0.55–3.21)

0.527

  

Yes

26 (22.8)

88 (77.2)

1

   

Length of hospital stay*

<=2 days

14 (31.1)

31 (68.9)

1

   

3–4 days

17 (24.6)

52 (75.4)

1.38 (0.60–3.19)

0.449

1.76 (0.65–4.77)

0.268

>=5 days

5 (8.3)

55 (91.7)

4.97 (1.63–15.10)

0.005

6.39 (1.75–23.27)

0.005

  1. * Variables included in multivariate logistic regression