Fig. 2
From: Rituximab as possible therapy in TNF inhibitor-induced IgA vasculitis with severe renal involvement
Kidney biopsy findings in patient 1 (A, B) and patient 2 (C, D). Light microscopy image showing a glomerulus with thickened capillary loops and the presence of a cellular crescent (arrow) (A, periodic acid-Schiff stain x20). Immunofluorescence staining revealed immunoglobulin A dominant deposits in the mesangium (B, immunofluorescence x20). Acute tubular necrosis (white arrows), glomerulus with cellular crescent (black arrow) and fibrinoid necrosis (C, periodic acid-Schiff stain x20). Presence of immunoglobulin A mesangial deposits (D, immunofluorescence x20)