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Table 1 Literature review of reported cases of IgA vasculitis with renal involvement during TNF inhibitor therapy. ANA: anti-nuclear antibodies; CS: corticosteroids; CYC: cyclophosphamide; MMF: mycophenolate mofetil; N/A: not available

From: Rituximab as possible therapy in TNF inhibitor-induced IgA vasculitis with severe renal involvement

Author, year

Number of cases

TNF inhibitor

Serology positivity

Withdrawal of TNF inhibitor

Treatment

Outcome

Duffy et al., 2006 [14]

1

Etanercept

ANA

Yes

CS, CYC

Good response

Sokumbi et al., 2012 [15]

1

Infliximab

N/A

Yes

CS, MMF

No response

Rolle et al., 2013 [16]

1

Etanercept

ANA, anti-histone

Yes

CS

Good response

Hokama et al., 2019 [17]

1

Adalimumab

Negative tests

Yes

CS

Good response

Fukuda et al., 2023 [18]

1

Infliximab

N/A

Yes

CS

Good response