Table 3 % change in terms of variables relevant to the 6H syndrome
Variable | Iron group (n) | Mean/Median (SD/IQR) | p-value |
|---|---|---|---|
iFGF23 | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | 3.0 (28.9) | |
FCM (11) | 146.1 (94.9) | < 0.001 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | 11.9 (40.6) | |
FCM (10) | 24.3 (52.7) | 0.284 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | 6.5 (30.3) | |
FCM (11) | 17.1 (32.3) | 0.566 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | 3.2 (28.9) | |
FCM (10) | 235.1 (296.1) | 0.001 | |
Baseline to 2 months after 1st infusion | FDI (12) | 15.7 (104.7) | |
FCM (10) | 8.1 (62.1) | 0.497 | |
Phosphate | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | -6.5 (15.1) | |
FCM (11) | -3.3 (18.2) | 0.893 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | -1.6 (20.6) | |
FCM (10) | -11.0 (17.8) | 0.077 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | -7.5 (25.1) | |
FCM (11) | -6.1 (14.3) | 1.000 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | 1.8 (30.3) | |
FCM (10) | -14.9 (14.7) | 0.013 | |
Baseline to 2 months after 1st infusion | FDI (13) | 9.2 (25.1) | |
FCM (10) | -13.2 (18.5) | 0.131 | |
Calcium a | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | 1.5 (2.7) | |
FCM (11) | 0.4 (2.5) | 0.297 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | 0.4 (3.4) | |
FCM (10) | -1.8 (3.1) | 0.131 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | 0.5 (2.9) | |
FCM (11) | 0.3 (3.8) | 0.916 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | 1.5 (2.2) | |
FCM (10) | -1.0 (2.4) | 0.035 | |
Baseline to 2 months after 1st infusion | FDI (12) | 0.5 (4.7) | |
FCM (10) | 1.5 (3.2) | 0.566 | |
Fractional excretion of phosphate | |||
Baseline to 1–2 days after 1st infusion | FDI (11) | -7.1 (26.2) | |
FCM (10) | 6.4 (27.9) | 0.314 | |
Baseline to 2 weeks after 1st infusion | FDI (12) | -3.7 (18.1) | |
FCM (10) | -5.0 (28.9) | 0.872 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (9) | -2.7 (13.0) | |
FCM (10) | 3.6 (33.9) | 0.661 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | -8.2 (31.6) | |
FCM (10) | 13.0 (48.4) | 0.182 | |
Baseline to 2 months after 1st infusion | FDI (10) | 5.0 (24.8) | |
FCM (10) | 0.3 (28.0) | 1.000 | |
1,25 (OH)2 Vitamin D a | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | -2.8 (14.2) | |
FCM (11) | -15.6 (12.8) | 0.027 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | -14.7 (14.6) | |
FCM (10) | -18.1 (14.9) | 0.580 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | -9.8 (16.5) | |
FCM (11) | -5.4 (27.2) | 0.642 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | -4.7 (13.0) | |
FCM (10) | -24.9 (22.5) | 0.031 | |
Baseline to 2 months after 1st infusion | FDI (12) | -5.4 (30.5) | |
FCM (10) | -5.3 (29.1) | 0.933 | |
25 (OH)2 Vitamin D | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | 1.6 (14.0) | |
FCM (11) | -3.5 (17.5) | 0.267 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | 5.8 (17.7) | |
FCM (10) | -0.3 (10.6) | 0.483 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | -11.0 (28.8) | |
FCM (11) | -7.1 (26.0) | 0.880 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | 0.8 (20.0) | |
FCM (10) | -8.5 (21.7) | 0.549 | |
Baseline to 2 months after 1st infusion | FDI (12) | -1.0 (48.8) | |
FCM (10) | -3.0 (25.7) | 0.923 | |
24(R), 25 (OH)2 Vitamin D | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | 0.0 (7.7) | |
FCM (11) | -8.3 (14.3) | 0.085 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | 0.0 (7.3) | |
FCM (10) | 12.0 (21.1) | 0.067 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | -4.2 (29.3) | |
FCM (11) | 13.5 (37.5) | 0.695 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | -3.0 (21.6) | |
FCM (10) | 6.3 (27.8) | 0.842 | |
Baseline to 2 months after 1st infusion | FDI (12) | 0.0 (48.4) | |
FCM (10) | -4.1 (26.8) | 0.923 | |
PTH a | |||
Baseline to 1–2 days after 1st infusion | FDI (14) | -7.8 (22.0) | |
FCM (11) | -6.9 (25.4) | 0.927 | |
Baseline to 2 weeks after 1st infusion | FDI (13) | 2.9 (30.8) | |
FCM (10) | 19.6 (32.9) | 0.226 | |
Baseline to 1 month after 1st infusion (2nd infusion) | FDI (12) | -12.1 (32.0) | |
FCM (11) | 13.6 (27.7) | 0.054 | |
Baseline to 1–2 days after 2nd infusion | FDI (9) | -3.7 (29.5) | |
FCM (10) | -5.0 (24.3) | 0.913 | |
Baseline to 2 months after 1st infusion | FDI (12) | 1.8 (36.7) | |
FCM (10) | -1.6 (28.1) | 0.810 | |