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Fig. 1 | BMC Nephrology

Fig. 1

From: A case of unexpected diagnosis of fibronectin glomerulopathy with histological features of membranoproliferative glomerulonephritis

Fig. 1

Light and electron microscopic examination. A and B Diffuse mesangial cell proliferation and increased mesangial matrix (HE and PAS staining, respectively, × 200). C PAM staining revealed thickening of the basement membrane with extensive mesangial infiltration and doubling. The lobulated segment exhibited scattered areas with methenamine silver-negative staining. (× 200). D MT staining showed a mild enhancement of trichrome red consistent with the lobulated region (× 200). E Congo-red staining yielded negative results. F Fibronectin (IST-4) staining exhibited a diffuse positive signal in the glomeruli, predominantly in the mesangial region (× 200). HE, hematoxylin and eosin staining; PAS, periodic acid-Schiff; PAM, periodic acid-methenamine-silver; MT, Masson trichrome staining

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BMC Nephrology

ISSN: 1471-2369

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