Table 1 Characteristics of studies included in this review.
Study ID | Year | Country | Study Design | Sample size | Age | Gender | Time of hemodialysis (months) | Intervention | Duration | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Treatment | Control | Treatment | Control | Treatment | Control | Treatment | Control | ||||||
Djuric, et al. | 2020 | Serbia | RCT | 26 | 29 | 63.8 ± 13.2 | 64.1 ± 9.7 | 17 M,13 F | 21 M,9 F | 104.4 ± 80.5 | 103.7 ± 75.1 | sodium thiosulfate 25 g/1.73 m2 iv three times a week | 6 months |
Saengpanit, et al. | 2018 | Thailand | RCT | 24 | 25 | 50.4 ± 9.5 | 54.4 ± 10.7 | 12 M,12 F | 16 M,10 F | 72.3 ± 56.7 | 62 ± 55.8 | sodium thiosulfate 12.5 g twice a week | 6 months |
Yu, et al. | 2016 | China | RCT | 15 | 10 | NA | NA | NA | NA | NA | NA | sodium thiosulfate 0.18Â g/kg iv 3 times a week | 3 months |
Hashiba, et al. | 2006 | Japan | RCT | 12 | 9 | 63.2 ± 3.33 | 67.7 ± 5.29 | NA | NA | 73.8 ± 22.7 | 63.6 ± 18.1 | Etidronate 200 mg/day | 12 months |
Hashiba, et al. | 2004 | Japan | RCT | 8 | 10 | 69.5 ± 3.2 | 62.1 ± 4.31 | NA | NA | NA | NA | Etidronate 200 mg/day | 6 months |
Ariyoshi, et al. | 2006 | Japan | RCT | 8 | 6 | 63.5 ± 8.3 | 66.3 ± 5.1 | 5 M,1 F | 5 M,1 F | NA | NA | Etidronate 400 mg/day | 6 months |
Fishbane, et al. | 2008 | USA | RCT | 87 | 86 | 57.7 ± 14.9 | 59.0 ± 12.4 | 52 M,35 F | 45 M,41 F | 46.3 ± 36.4 | 46.8 ± 44.1 | Cinacalcet start with 30 mg/d, then adjusted to achieve targets | 4 months |
Ureña-Torres, et al. | 2013 | France | RCT | 153 | 151 | 57.9 ± 13.6 | 57 ± 14.6 | 83 M,70 F | 95 M,56 F | 7.29 ± 2.54 | 7.02 ± 2.78 | Cinacalcet start with 30 mg/d, then adjusted to achieve targets | 12 months |
Eddington, et al. | 2021 | UK | RCT | 15 | 19 | 45 ± 16 | 54 ± 13 | 11 M,4 F | 12 M,3 F | 97.75 ± 89.97 | 103.75 ± 60.94 | Cinacalcet start with 30 mg/d, then adjusted to achieve targets | 12 months |
Susantitaphong et al. | 2019 | Thailand | RCT | 15 | 15 | 49.5 ± 11.9 | 49.4 ± 10.2 | 12 M,3 F | 7 M,8 F | 79.2 ± 43.2 | 84.0 ± 60.0 | Cinacalcet start with 25 mg/d, then ajusted to achieve targets | 3 months |
Raggi, et al. | 2011 | USA | RCT | 180 | 180 | 61.2 ± 12.6 | 61.8 ± 12.8 | 112 M,68 F | 95 M,85 F | 47.33 ± 17.72 | 47.73 ± 18.05 | Cinacalcet start with 30 mg/d, then adjusted to achieve targets | 12 months |