Table 2 Clinical characteristics of the training group
Characteristics | All patientss (n = 187) | Control group(n = 125) | Accumulation group (n = 62) | Z/χ2 | P-value |
|---|---|---|---|---|---|
Age (years) | 56(46, 66) | 54(43,63) | 62(53.25,70) | −3.06 | 0.002 |
Male【n(%)】 | 128(68.4) | 91(72.8) | 37(59.7) | 2.542 | 0.069 |
Hepatic dysfunction classification【n(%)】 | 4.793 | 0.309 | |||
acute hepatic failure | 52(27.8) | 39(31.2) | 13(21) | ||
subacute hepatic failure | 3(1.6) | 1(0.8) | 2(3.2) | ||
acute-on-chronic hepatic failure | 37(19.8) | 21(16.8) | 16(25.8) | ||
chronic hepatic failure | 34(18.2) | 23(18.4) | 11(17.7) | ||
hepatic dysfunction | 61(32.6) | 41(32.8) | 20(32.3) | ||
Indications for CRRT 【n(%)】 | 0.586 | 0.746 | |||
CKD | 11(5.9) | 8(6.4) | 3(4.7) | ||
AKI | 129(69) | 84(67.2) | 45(72.6) | ||
Others | 47(25.1) | 33(26.4) | 14(21.9) | ||
APACHE II scores | 23.6 ± 6.18 | 22.53 ± 5.85 | 25.73 ± 5.80 | −3.415 | 0.001 |
MELD scores | 22.8(20.45,25.60) | 26.5(21,31) | 30(24,34) | −3.297 | 0.001 |
SOFA | 12(10,14) | 12(10,14) | 12.5(10,15) | −0.892 | 0.375 |
Child-pugh | 9(8,11) | 9(7.5,10.5) | 10(8,11) | −1.701 | 0.089 |
BMI (kg/m^2) | 22.7(20.3,25.60) | 22.85(20.48,25.6) | 22.4(19.6,25.6) | −0.253 | 0.801 |
Weight (kg) | 62.75(55,70) | 63(55,71) | 60(50,70) | −1.448 | 0.148 |
Map (mmHg) | 81(74,89) | 81(75,89) | 78(71,86.25) | −2.342 | 0.019 |
Norepinephrine (ug/kg/min) | 0.02(0, 0.16) | 0.00(0,0.11) | 0.08(0, 0.2) | −2.299 | 0.016 |
Alb (g/L) | 33.1(29.3,36.6) | 33.1(29.4,37.6) | 32.9(29.3,35.50) | −0.818 | 0.413 |
AST (U/L) | 127(53, 438) | 143(54.5548.3) | 107(44.5325.5) | −1.108 | 0.268 |
ALT (U/L) | 102(33, 387) | 122(35,459) | 55(29.5231.8) | −1.623 | 0.105 |
LDH (U/L) | 399(284,758) | 395(273,736) | 403(296, 857) | −0.353 | 0.724 |
Tbil (umol/L) | 130(57,257) | 126.4(55.6239.4) | 138.3(60.9320.8) | −0.796 | 0.426 |
CRP (mg/L) | 53.26(20.15,101.55) | 53.7(23.6101.9) | 43.8(16.9100.9) | −1.020 | 0.308 |
WBC(*10^9/L) | 9.65(6.5,15.24) | 9.85(6.49,15.67) | 9.34(6.57,13.92) | −0.065 | 0.949 |
PLT(*10^9/L) | 46(29,106) | 52(30,121) | 40(27.25,83.5) | −1.894 | 0.058 |
Hb(g/L) | 73(62,93) | 73(60,96) | 71.5(63,92.25) | −0.675 | 0.5 |
PT(s) | 18.1(14.6,24.3) | 17.4(14.6,23.1) | 19.8(15.4,27) | −1.765 | 0.078 |
INR | 1.64(1.28,2.22) | 1.54(1.26,2.12) | 1.93(1.32,2.62) | −2.292 | 0.022 |
APTT(s) | 44.1(33.2,60.1) | 43.1(33.2,67.3) | 46.4(33.2,67.3) | −1.280 | 0.201 |
serum potassium (mmol/L) | 4.32(4,4.67) | 4.34(3.99,4.69) | 4.32(4.06,4.62) | −0.323 | 0.747 |
tCa (mmol/L) | 2.25(2.17,2.25) | 2.23(2.16, 2.36) | 2.27(2.20,2.45) | −2.173 | 0.03 |
Scr (umol/L) | 168(87,255) | 158(78, 254) | 175(94.5267) | −1.423 | 0.155 |
BUN (mmol/L) | 14.6(7.9,14.6) | 13.5(7.59,20.74) | 15.11(7.68,23.55) | −1.082 | 0.279 |
pH | 7.43(7.38,7.47) | 7.43(7.38,7.46) | 7.45(7.39,7.48) | −1.735 | 0.083 |
PO2 (mmHg) | 106(89,132) | 113(91,139) | 99.5(80,118) | −2.569 | 0.01 |
PCO2 (mmHg) | 34.8(31.6,39.2) | 35(32,40.03) | 33.9(30.65,38.55) | −1.613 | 0.107 |
Bicarbonate concentration (mmol/L) | 23.16 ± 3.8 | 23 ± 4.05 | 23.2 ± 3.3 | −0.079 | 0.937 |
BE (mmol/L) | −1.15 ± 4.13 | −1.3 ± 4.38 | −0.93 ± 3.65 | − 0.506 | 0.613 |
Lactate (mmol/L) | 1.9(1.3,3.1) | 1.8(1.2,2.8) | 2.2(1.3,3.9) | −1.515 | 0.13 |
iCa (mmol/L) | 1.12(1.04,1.18) | 1.12(1.04,1.17) | 1.11(1.03,1.18) | −0.154 | 0.879 |
Dialysate flow rate (ml/h) | 1000(1000,2000) | 1000(1000,2000) | 1000(1000,2000) | −2.089 | 0.037 |
replacement flow rate (ml/h) | 1000(1000,1000) | 1000(1000,1000) | 1000(1000,1000) | −0.329 | 0.742 |
CRRT dosage (ml/h/kg) | 38(31,50) | 40(32,50) | 37(30,48) | −0.897 | 0.370 |
Citrate concentration (mmol/L) | 3(2,3) | 2.5(2,3) | 3(2.5,3) | −2.792 | 0.005 |