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Table 2 Cox regression model eGFR hazard ratios for all-cause and CVD mortality among patients with type 2 diabetes stratified by age using 65 years as cut-off and gender, with eGFR between 90 and 119 mL/min per 1.73 m2 as reference (N = 36,556; years 2013–2019)

From: Heterogeneity by age and gender in the association of kidney function with mortality among patients with diabetes - analysis of diabetes registry in Singapore

eGFR categories (mL/min per 1.73 m2)

< 65 years

≥65 years

Number of Deaths (incidence rate (%) Malea)

Hazard Ratio (95% CI) Male

Number of Deaths (incidence rate (%) Femalea)

Hazard Ratio (95% CI) Female

Number of Deaths (incidence rate (%) Malea)

Hazard Ratio (95% CI) Male

Number of Deaths (incidence rate (%) Femalea)

Hazard Ratio (95% CI) Female

All-cause mortality

        

 < 30

2 (31.25)

6.63 (1.64, 26.70)

5 (64.94)

22.88 (9.36, 55.94)

32 (66.12)

4.19 (2.86, 6.13)

42 (51.92)

6.90 (4.89, 9.74)

 30 - < 60

17 (7.13)

1.44 (0.88, 2.38)

18 (9.23)

3.01 (1.84, 4.94)

333 (33.89)

2.05 (1.69, 2.47)

270 (23.65)

3.03 (2.47, 3.71)

 60 - < 90

103 (5.54)

1.12 (0.88, 1.43)

53 (5.17)

1.68 (1.22, 2.32)

536 (20.19)

1.20 (1.00, 1.44)

489 (16.30)

2.06 (1.71, 2.49)

 90 - < 120

172 (4.95)

1.00 (Reference)

127 (3.08)

1.00 (Reference)

152 (16.90)

1.00 (Reference)

141 (7.99)

1.00 (Reference)

CVD mortality

        

 < 30

1 (15.63)

9.58 (1.33, 69.14)

3 (38.96)

59.64 (18.16, 195.91)

9 (18.60)

4.72 (2.28, 9.79)

17 (21.01)

14.43 (7.87, 26.48)

 30 - < 60

8 (3.35)

1.98 (0.95, 4.15)

7 (3.59)

5.13 (2.25, 11.71)

95 (9.67)

2.38 (1.63, 3.48)

88 (7.71)

5.13 (3.33, 7.89)

 60 - < 90

37 (1.99)

1.17 (0.78, 1.77)

12 (1.17)

1.67 (0.85, 3.27)

143 (5.39)

1.31 (0.91, 1.88)

118 (3.93)

2.59 (1.71, 3.94)

 90 - < 120

59 (1.70)

1.00 (Reference)

29 (0.70)

1.00 (Reference)

37 (4.11)

1.00 (Reference)

27 (1.53)

1.00 (Reference)

  1. Unadjusted model: Abbreviations: eGFR estimated glomerular filtration rate, CVD cardiovascular disease
  2. aThe incidence rate represented is for per 1000 person-years