Table 2 Pathological characteristics of IgAN and IgAVN patients
IgAN | IgAVN | P value | |
|---|---|---|---|
Number of glomeruli | 19.21 ± 8.93 | 22.14 ± 9.94 | 0.007 |
Cellular crescents (n, %) | 58 (23%) | 23 (38%) | 0.011 |
Fibrocellular or fibrous crescents (n, %) | 174 (68.8%) | 28 (39.4%) | < 0.001 |
Endothelial cell proliferation (n, %) | 30 (11.9%) | 14 (19.7%) | 0.088 |
Mesangial cell proliferation (n, %) | 250 (98.8%) | 71(100%) | > 0.999 |
Glomerular sclerosis (n, %) | 155(61.3%) | 23(32.4%) | < 0.001 |
Interstitial inflammatory cell infiltration (n, %) | 143(56.5%) | 17(23.9%) | < 0.001 |
Interstitial fibrosis/tubular atrophy (n, %) | 134 (53%) | 12 (16.9%) | < 0.001 |
Thickness of blood vessel wall (n, %) | 155(61.3%) | 20(28.2%) | < 0.001 |
Activity index | 2.27 ± 1.22 | 2.38 ± 1.56 | 0.326 |
Chronicity index | 2.34 ± 1.81 | 1.03 ± 1.24 | < 0.001 |
Total biopsy score | 5.24 ± 2.63 | 3.69 ± 2.59 | < 0.001 |