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Fig. 2 | BMC Nephrology

Fig. 2

From: Effects of CYP3A4*22 and POR*28 variations on the pharmacokinetics of tacrolimus in renal transplant recipients: a meta-analysis of 18 observational studies

Fig. 2

Forest plots illustrating the relationship between CYP3A4 genetic variants and tacrolimus pharmacokinetics. A Weight-adjusted daily dose of CYP3A4*1/*1 carriers versus CYP3A4*22 carriers at different post-transplantation time courses; B C0/Dose of CYP3A4*1/*1 carriers versus CYP3A4*22 carriers at different post-transplantation time courses. C0/Dose: dose-adjusted trough concentration; NR: not reported; WMD: weighted mean difference; SMD: standard mean difference; CI: confidence interval; d: days; mon: months

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