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Table 1 Demographic, WMH scores and CBF of the study participants

From: Association between white matter hyperintensities and altered cerebral blood flow in maintenance hemodialysis patients: a longitudinal study

 

Hemodialysis baseline group (n = 33)

Hemodialysis follow-up group (n = 33)

HC group (n = 33)

P

Age (years)

53.7 ± 10.1

56.7 ± 10.1

51.8 ± 8.8

0.121

Sex (male/female)

20/13

20/13

20/13

1.000

Hemodialysis duration (months)

84.4 ± 68.6

120.2 ± 68.9

NA

NA

dWMH score

1(0,2)

1(1,2)

0(0,1)

0.000

pWMH score

1(1,2)

1(1,2)

1(1,1)

0.002

Up-level CW-WMH score

1(0,1)

1(0,2)

0(0,1)

0.001

Lower-level CW-WMH score

1(0,2)

1(0,2)

0(0,1)

0.000

Total CW-WMH score

1(0,3)

2(1,4)

0(0,1.5)

0.000

Grey matter CBF (ml/100 g/min)

44.638 ± 9.161

44.784 ± 7.946

47.723 ± 8.433

0.258

White matter CBF (ml/100 g/min)

39.423 ± 7.678

40.575 ± 7.148

40.252 ± 6.156

0.790

Whole matter CBF (ml/100 g/min)

41.997 ± 8.565

42.719 ± 7.320

44.611 ± 7.655

0.382

Pre-dialysis MAP (mmHg)

96.5 ± 10.1

98.1 ± 12.1

NA

0.076

Post-dialysis MAP (mmHg)

99.3 ± 11.9

98.9 ± 11.1

NA

0.632

Hb (g/L)

116.5 ± 11.6

117.6 ± 11.6

NA

0.754

UFR (mL/h)

679.4 ± 164.5

682.4 ± 156.7

NA

0.456

ALB (g/L)

38.0 ± 2.7

38.4 ± 2.8

NA

0.162

hs-CRP (mg/L)

3.2 (1.4–8.6)

2.9 (1.4–8.9)

NA

0.487

  1. Data are presented as the mean ± standard deviation, median (upper and lower quartiles)
  2. WMH = white matter hyperintensities; CBF = cerebral blood flow; HC = healthy controls; NA = not applicable; dWMH = deep white matter hyperintensities; pWMH = periventricular white matter hyperintensities; CW-WMH = cerebral watershed white matter hyperintensities; MAP = Mean arterial pressure; UFR = ultrafiltration rate; ALB = albumin hs-CRP = hypersensitive C-reactive protein