Fig. 4From: Longitudinal NGAL and cystatin C plasma profiles present a high level of heterogeneity in a mixed ICU populationPlasma NGAL and Cystatin C during first 6 days of ICU admission based on maximum KDIGO score. KDIGO AKI score based on serum creatinine and urine output [5]. Individual biomarker plasma values, plus median and Interquartile Range (IQR) plotted. Prognostic and diagnostic cut off values calculated based on ROC and Youden’s principle. Prognostic cut off value based on biomarker levels 1 day prior to AKI diagnosis. Diagnostic cut off value based on biomarker levels on day of AKI diagnosis. ** p < 0.001, * p < 0.05Back to article page