Table 3 Clinical characteristics of participants in the KIND registry (n = 2,912)
Variable | Male | Female | Total |
|---|---|---|---|
N (%) | |||
Diabetes Mellitus (ICD10: E10, E11, and E13) | |||
 No | 962 (58.4) | 703 (55.6) | 1,665 (57.2) |
 Yes | 685 (41.6) | 562 (44.4) | 1,247 (42.8) |
Hypertension (ICD10: I10-I15) | |||
 No | 802 (48.7) | 598 (47.3) | 1,400 (48.1) |
 Yes | 845 (51.3) | 667 (52.7) | 1,512 (51.9) |
Coronary artery disease (ICD10: I20-I25) | |||
 No | 1,591 (96.6) | 1,242 (98.2) | 2,833 (97.3) |
 Yes | 56 (3.4) | 23 (1.8) | 79 (2.7) |
Smoking status | |||
 No | 266 (16.2) | 273 (21.6) | 539 (18.5) |
 Yes | 10 (0.6) | 2 (0.2) | 12 (0.4) |
 Unknown | 1,371 (83.2) | 990 (78.3) | 2,361 (81.1) |
Classification of patients (based on kidney disease or KRT) | |||
 Glomerulonephritis | 163 (9.9) | 131 (10.4) | 294 (10.1) |
 ESKD on dialysis | 449 (27.3) | 466 (36.8) | 915 (31.4) |
 ESKD Post-transplant | 441 (26.8) | 278 (22.0) | 719 (24.7) |
 More than one typea | 594 (36.1) | 390 (30.8) | 984 (33.8) |
 Mean age (in years) at onset of symptoms (SD) | 37.32 (17.6) | 37.88 (18.3) | 37.55 (17.9) |
 Mean age (in years) at biopsy (SD) | 38.25 (17.7) | 38.23 (18.2) | 38.24 (17.9) |
Cause of CKD | |||
 Diabetic Nephropathy (ICD-10: E1021, E1022, E1121, E1122, E1322) | 559 (33.9) | 466 (36.8) | 1,025 (35.2) |
 Glomerulonephritis (ICD10: N50-N59) | 288 (17.5) | 214 (16.9) | 502 (17.2) |
 Hypertensive renal disease (ICD-10: I120, I129-I132) | 219 (13.3) | 150 (11.9) | 369 (12.7) |
 Pyelonephritis (ICD10: N10, N12, and N119) | 6 (0.4) | 6 (0.5) | 12 (0.4) |
 Polycystic kidney disease (ICD10: Q613) | 8 (0.5) | 2 (0.2) | 10 (0.3) |
 Reflux nephropathy (ICD-10: N137) | 4 (0.2) | 6 (0.5) | 10 (0.3) |
 Calculi (ICD-10: N20.0 and N200) | 7 (0.4) | 2 (0.2) | 9 (0.3) |
 Unknown | 407 (24.7) | 305 (24.1) | 712 (24.5) |
 Others (ICD10: N12, N170, I129, Q611, and M1036) | 7 (0.4) | 9 (0.7) | 16 (0.6) |
Multiple causes from those listed above | 142 (8.6) | 105 (8.3) | 247 (8.5) |
Biopsy details | |||
 No biopsy taken | 1,299 (78.9) | 1,026 (81.1) | 2,325 (79.8) |
 Biopsy was taken at NGHA | 348 (21.1) | 239 (18.9) | 587 (20.2) |
Family History of Glomerulonephritis | |||
 No | 328 (19.9) | 231 (18.3) | 559 (19.2) |
 Yes | 7 (0.4) | 5 (0.4) | 12 (0.4) |
 Unknown | 1,312 (79.7) | 1,029 (81.3) | 2,341 (80.4) |
Dialysis History | |||
Ever on dialysis | |||
 No | 648 (39.3) | 435 (34.4) | 1,083 (37.2) |
 Yes | 999 (60.7) | 830 (65.6) | 1,829 (62.8) |
Type of initial dialysis modality (if ever on dialysis) | |||
 Hemodialysis (HD) | 924 (92.5) | 730 (88.0) | 1,654 (90.4) |
 Peritoneal dialysis (PD) | 61 (6.1) | 83 (10.0) | 144 (7.9) |
 Hemodiafiltration | 0 (0.0) | 2 (0.2) | 2 (0.1) |
 Missing | 14 (1.4) | 15 (1.8) | 29 (1.6) |
Type of hemodialysis | |||
 High flux | 518 (56.1) | 490 (67.1) | 1,008 (60.9) |
 Low flux | 3 (0.3) | 3 (0.4) | 6 (0.4) |
 Missing | 403 (43.6) | 237 (32.5) | 640 (38.7) |
Type of Peritoneal dialysis | |||
 Continuous ambulatory PD | 5 (8.2) | 8 (9.6) | 13 (9.0) |
 Continuous cyclic PD | 1 (1.6) | 9 (10.8) | 10 (6.9) |
 Nocturnal intermittent PD | 1 (1.6) | 2 (2.4) | 3 (2.1) |
 Missing | 54 (88.5) | 64 (77.1) | 118 (81.9) |