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Table 1 Eligibility criteria

From: Mortality risk in patients with autosomal dominant polycystic kidney disease

Cohort

Inclusion criteria

ADPKD Non-ESRD CKD

▪ Had at least 2 records with an ADPKD diagnosis code (ICD-9-CM codes: 753.13, 753.12; ICD-10-CM codes: Q61.2, Q61.3) in the CKD database across all available years

▪ Was included in the 2014, 2015, or 2016 CKD cohort, as defined by the researcher’s guide [22] as having met both of the following criteria:

• For the entire year, the patient was Part A and Part B entitled and was not enrolled in a health maintenance organization

• The patient had at least 1 CKD diagnosis code from an inpatient or home health or skilled nursing facility SAF, or at least 2 CKD diagnosis codes from a physician or supplier, durable medical equipment, or outpatient SAF with different claim dates

▪ The patient was alive and did not receive ESRD services as of 1 January 2014

ADPKD ESRD

▪ Had at least 1 ADPKD diagnosis code (ICD-9-CM codes: 753.13, 753.12; ICD-10-CM codes: Q61.2, Q61.3) reported in the ESRD Medical Evidence Report form [20] as the primary cause of renal failure

▪ First ESRD service date was on or before 1 December 2016 so that each patient would have at least 1 month of follow-up before the end of the study period

▪ Was alive (based on the death date) as of 1 January 2014

▪ Had no flag for a data issue

  1. ADPKD Autosomal dominant polycystic kidney disease, CKD Chronic kidney disease, ESRD End-stage renal disease, ICD-9-CM International Classification of Diseases, Ninth Edition, Clinical Modification, ICD-10-CM International Classification of Diseases, Tenth Edition, Clinical Modification, SAF Standard Analytic File (CMS)