Skip to main content

Table 5 Adjusted hazard ratios among ADPKD patients aged 65 years and older

From: Mortality risk in patients with autosomal dominant polycystic kidney disease

Non-ESRD CKD

ESRD

Characteristic

Category

Adjusted HR (95% CI)

P value

Characteristic

Category

Adjusted HR (95% CI)

P value

Stage

Stage 1

0.28 (0.04–2.01)

0.2058

Treatment

Dialysis

1.92 (1.78–2.07)

 < 0.0001

Stage 2

0.71 (0.35–1.47)

0.3588

Transplant

Reference

N/A

Stage 3

Reference

N/A

Stage 4

1.60 (1.12–2.29)

0.0096

Stage 5

1.85 (0.75–4.60)

0.1837

Age group

65–74 years

Reference

N/A

Age group

65–74 years

Reference

N/A

75–84 years

1.70 (1.13–2.55)

0.0108

 

75–84 years

1.83 (1.69–1.98)

 < 0.0001

85 years and older

3.43 (2.27–5.19)

 < 0.0001

 

85 years and older

3.04 (2.67–3.46)

 < 0.0001

Sex

Female

0.77 (0.55–1.07)

0.1178

Sex

Female

0.93 (0.87–1.00)

0.0419

Male

Reference

N/A

Male

Reference

N/A

Race

Black

1.41 (0.90–2.21)

0.1377

Race

Black

0.87 (0.77–0.97)

0.0150

Hispanic

1.22 (0.30–4.93)

0.7847

Hispanic

0.69 (0.60–0.80)

 < 0.0001

Asian

1.48 (0.60–3.65)

0.3925

Asian

0.71 (0.57–0.89)

0.0025

Other or unknown a

0.53 (0.13–2.14)

0.3709

Other or unknown a

0.77 (0.51–1.17)

0.2228

White

Reference

N/A

White

Reference

N/A

  1. ADPKD Autosomal dominant polycystic kidney disease, CI Confidence interval, CKD Chronic kidney disease, ESRD End-stage renal disease, HR Hazard ratio, N/A Not applicable, USRDS United States Renal Data System
  2. Notes: Adjusted HRs were estimated from the Cox model, including treatment, age group, sex, and race. Age and treatment were determined at study entry (start of patient-time at risk)
  3. a In addition to “White,” “Black,” “Hispanic,” and “Asian” in the non-ESRD CKD USRDS dataset, “race” also included “Native American,” “Other,” and “Unknown,” which have been grouped in this table as “Other or unknown.” In addition to “White,” “Black/African American” (referred to as “Black” in this table), “Hispanic,” and “Asian” in the ESRD USRDS dataset, “race” also included “American Indian or Alaska Native,” “Native Hawaiian or Pacific Islander,” “Other or Multiracial,” and Unknown, which have been grouped in this table as “Other or unknown.”
Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us