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Fig. 2 | BMC Nephrology

Fig. 2

From: Assessing the effects of tempol on renal fibrosis, inflammation, and oxidative stress in a high-salt diet combined with 5/6 nephrectomy rat model: utilizing oxidized albumin as a biomarker

Fig. 2

Biochemical testing parameters. (a)(b)Serum creatinine and BUN. Serum creatinine and BUN levels were higher in rats fed a high-salt diet compared to those on a normal-salt diet. However, rats in the Treatment group had lower serum creatinine and BUN levels compared to the high-salt diet group. (c) 8-OHdG. The high-salt diet also led to increased serum 8-OHdG levels, but Tempol reversed this effect. (d) (e) (f) TGF-β1, mALB and urine creatinine. Administering Tempol improved oxidative stress in rats on a high-salt diet, as evidenced by normalized levels of TGF-β1, and mALB. However, these levels were still higher than in rats on a normal-salt diet. The values are shown as AVE ± SEM

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BMC Nephrology

ISSN: 1471-2369

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