From: Long-term ozone exposure and mortality in patients with chronic kidney disease: a large cohort study
Variables | Category | Total | Ozone (ppb) | p-value | |||
---|---|---|---|---|---|---|---|
Q1 [ 5 -27.54) | Q2 [ 27.54–31.78) | Q3 [ 31.78–35.38) | Q4 [ 35.38–199.63) | ||||
N | 56,470 | 14,117 | 14,117 | 14,118 | 14,118 | Â | |
Missing | 4603 | Â | Â | Â | Â | Â | |
Outcomes | |||||||
 End-stage renal disease (ESRD) | N | 5957 | 1513 | 1432 | 1478 | 1534 | 0.2144 |
  Follow up duration (ESRD) | Mean ± SD | 71.64 ± 52.96 | 107.85 ± 59.82 | 83.45 ± 50.31 | 56.37 ± 40.65 | 42.03 ± 36.38 |  |
 All-cause mortality | N | 6768 | 2193 | 1865 | 1523 | 1182 |  < 0.001 |
  Follow up duration (Mortality) | Mean ± SD | 82.12 ± 51.67 | 119.93 ± 54.20 | 99.04 ± 44.89 | 64.69 ± 39.70 | 47.21 ± 36.61 |  |
  NO2 | Mean ± SD | 33.60 ± 6.54 | 39.29 ± 15.32 | 36.75 ± 14.02 | 34.82 ± 14.12 | 28.17 ± 13.80 |  < 0.001* |
  PM10 | Mean ± SD | 56.79 ± 9.05 | 60.24 ± 42.25 | 58.61 ± 33.41 | 54.06 ± 32.98 | 50.89 ± 29.92 |  < 0.001* |
  Age | Mean ± SD | 58.37 ± 17.37 | 62.00 ± 16.82 | 57.87 ± 17.38 | 58.17 ± 17.61 | 58.45 ± 17.22 |  < 0.001* |
Sex |  | 56,470 |  |  |  |  |  < 0.001 |
male | 29,961(48.82) | 6673(11.82) | 6693(11.85) | 6866(12.16) | 7335(12.99) | Â | |
female | 28,903(51.18) | 7444(13.81) | 7424(13.15) | 7252(12.84) | 6783(12.01) | Â | |
Education level (%) |  | 8423 |  |  |  |  |  < 0.001 |
Elementary | 3133 (15.59) | 1532 (6.54) | 725 (3.10) | 809 (3.45) | 828 (3.53) | Â | |
Middle-high | 9105(46.36) | 4131 (17.64) | 2079 (8.88) | 2228 (9.51) | 2539 (10.84) | Â | |
College, University | 7403 (37.69) | 3595 (15.35) | 1755 (7.49) | 1553 (6.63) | 1650 (7.04) | Â | |
missing | 41,432 | Â | Â | Â | Â | Â | |
Income level | Â | 19,641 | Â | Â | Â | Â | Â |
Low | 1668(19.80) | 348(4.13) | 394(4.68) | 445(5.28) | 481(5.71) | 0.307 | |
High | 6755(80.20) | 1553(18.44) | 1558(18.50) | 1776(21.09) | 1868(27.89) | Â | |
missing | 52,650 | Â | Â | Â | Â | Â | |
BMI |  | 56,470 | 23.25 ± 3.54 | 23.62 ± 3.75 | 23.58 ± 3.71 | 23.80 ± 3.82 |  < 0.001 |
BMI < 18.5 | 21,019(37.22) | 6082(10.77) | 5374(9.52) | 5009(8.87) | 4554(8.06) |  | |
18.5 ≤ BMI < 23 | 14,477(25.64) | 3545(6.28) | 3569(6.32) | 3650(6.46) | 3713(6.58) |  | |
23 ≤ BMI < 25 | 8526(15.10) | 1936(3.43) | 2118(3.75) | 2222(3.93) | 2250(3.98) |  | |
25 ≤ BMI | 12,448(22.04) | 2554(4.52) | 3056(5.41) | 3237(5.73) | 3601(6.38) |  | |
Diabetic Mellitus | No | 43,450(76.94) | 11,001(19.48) | 10,939(19.37) | 10,799(19.12) | 10,711(18.97) |  < 0.001 |
Yes | 13,020(23.06) | 3116(5.52) | 3178(5.63) | 3319(5.88) | 3407(6.03) | Â | |
missing | 4603 | Â | Â | Â | Â | Â | |
Hypertension | No | 44,132(78.15) | 11,861(21) | 10,710(18.97) | 10,564(18.71) | 10,997(19.47) |  < 0.001 |
Yes | 12,338(21.85) | 2256(4) | 3407(6.03) | 3554(6.29) | 3121(5.53) | Â | |
missing | 4603 | Â | Â | Â | Â | Â | |
e-GFR(mL/min/1.73 m2) |  | 61.07 ± 29.92 | 61.32 ± 27.35 | 61.42 ± 28.57 | 61.74 ± 30.39 | 60.32 ± 32.63 |  < 0.001* |
CKD stage |  < 30 | 9481(16.79) | 2142(3.79) | 2213(3.92) | 2374(4.2) | 2752(4.87) |  < 0.001 |
30–59 | 16,616(29.42) | 3872(6.86) | 4102(7.26) | 4238(7.5) | 4404(7.8) |  | |
60–89 | 21,702(38.43) | 6375(11.29) | 5789(10.25) | 5110(9..05) | 4428(7.84) |  | |
89 <  | 8671(15.36) | 1728(3.06) | 2013(3.56) | 2396(4.24) | 2534(4.49) |  | |
missing | 4603 | Â | Â | Â | Â | Â | |
Beds in medical facilities per 1,000 people |  | 8.75 ± 3.51 | 9.31 ± 3.83 | 8.68 ± 3.24 | 8.19 ± 2.66 | 9.03 ± 4.29 |  < 0.001* |
Financial independence |  | 52.17 ± 15.97 | 54.02 ± 15.76 | 54.93 ± 14.90 | 53.23 ± 15.4 | 45.40 ± 16.41 |  < 0.001* |