From: Long-term ozone exposure and mortality in patients with chronic kidney disease: a large cohort study
Outcomes | End-stage renal disease (ESRD) | All-cause morality | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Exposure assessments | Districts | Points | Districts | Points | ||||||||
HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |||||
Model | ||||||||||||
 Age | 1 | 0.999 | 1.002 | 1 | 0.998 | 1.003 | 1.068 | 1.066 | 1.07 | 1.06 | 1.057 | 1.063 |
 Male | 1.406 | 1.349 | 1.465 | 1.365 | 1.264 | 1.475 | 1.72 | 1.651 | 1.792 | 1.827 | 1.706 | 1.957 |
 Hypertension | 0.958 | 0.915 | 1.003 | 0.863 | 0.785 | 0.949 | 1.141 | 1.093 | 1.192 | 1.594 | 1.483 | 1.713 |
 Diabetic Mellitus | 2.629 | 2.517 | 2.747 | 2.371 | 2.187 | 2.571 | 1.524 | 1.462 | 1.588 | 1.409 | 1.315 | 1.509 |
 BMI < 18.5 | 0.266 | 0.25 | 0.282 | 0.289 | 0.257 | 0.324 | 0.745 | 0.709 | 0.782 | 0.879 | 0.812 | 0.952 |
 23 ≤ BMI < 25 | 0.628 | 0.593 | 0.665 | 0.634 | 0.57 | 0.705 | 0.605 | 0.57 | 0.642 | 0.571 | 0.517 | 0.63 |
 25 \(\le\) BMI | 0.552 | 0.524 | 0.581 | 0.578 | 0.524 | 0.636 | 0.526 | 0.496 | 0.557 | 0.419 | 0.379 | 0.463 |
 O3 (ppb) | 1.034 | 1.031 | 1.036 | 1.019 | 1.011 | 1.026 | 1.02 | 1.018 | 1.023 | 1.047 | 1.041 | 1.054 |
Model1 | ||||||||||||
 Age | 0.986 | 0.985 | 0.988 | 0.986 | 0.984 | 0.989 | 1.059 | 1.057 | 1.06 | 1.051 | 1.048 | 1.054 |
 Male | 1.214 | 1.165 | 1.265 | 1.212 | 1.122 | 1.309 | 1.608 | 1.544 | 1.675 | 1.701 | 1.589 | 1.821 |
 Hypertension | 0.963 | 0.92 | 1.008 | 0.8 | 0.728 | 0.879 | 1.142 | 1.094 | 1.193 | 1.576 | 1.467 | 1.693 |
 Diabetic Mellitus | 1.71 | 1.638 | 1.785 | 1.67 | 1.543 | 1.808 | 1.304 | 1.251 | 1.359 | 1.236 | 1.154 | 1.324 |
 BMI < 18.5 | 0.458 | 0.43 | 0.487 | 0.436 | 0.388 | 0.491 | 0.951 | 0.906 | 0.999 | 1.075 | 0.992 | 1.165 |
 23 ≤ BMI < 25 | 0.842 | 0.795 | 0.891 | 0.879 | 0.79 | 0.978 | 0.677 | 0.637 | 0.719 | 0.642 | 0.581 | 0.709 |
 25 \(\le\) BMI | 0.799 | 0.759 | 0.842 | 0.889 | 0.806 | 0.981 | 0.608 | 0.574 | 0.644 | 0.481 | 0.435 | 0.533 |
 e-GFR(mL/min/1.73 m2) | 0.929 | 0.928 | 0.931 | 0.927 | 0.925 | 0.929 | 0.972 | 0.971 | 0.973 | 0.974 | 0.973 | 0.976 |
 O3 (ppb) | 1.025 | 1.023 | 1.028 | 1.02 | 1.013 | 1.028 | 1.016 | 1.014 | 1.019 | 1.046 | 1.039 | 1.053 |
Model2 | ||||||||||||
 Age | 0.987 | 0.986 | 0.988 | 0.987 | 0.984 | 0.99 | 1.06 | 1.058 | 1.061 | 1.05 | 1.047 | 1.053 |
 Male | 1.216 | 1.165 | 1.269 | 1.193 | 1.097 | 1.297 | 1.591 | 1.524 | 1.66 | 1.671 | 1.553 | 1.798 |
 Hypertension | 0.929 | 0.887 | 0.974 | 0.778 | 0.705 | 0.858 | 1.077 | 1.03 | 1.126 | 1.537 | 1.427 | 1.656 |
 Diabetic Mellitus | 1.683 | 1.61 | 1.76 | 1.673 | 1.535 | 1.823 | 1.269 | 1.215 | 1.325 | 1.165 | 1.082 | 1.255 |
 BMI < 18.5 | 0.489 | 0.458 | 0.522 | 0.449 | 0.394 | 0.512 | 0.915 | 0.869 | 0.964 | 1.017 | 0.932 | 1.109 |
 23 ≤ BMI < 25 | 0.845 | 0.796 | 0.896 | 0.892 | 0.794 | 1.003 | 0.665 | 0.625 | 0.708 | 0.632 | 0.569 | 0.702 |
 25 \(\le\) BMI | 0.778 | 0.737 | 0.822 | 0.866 | 0.779 | 0.962 | 0.599 | 0.564 | 0.636 | 0.458 | 0.411 | 0.509 |
 e-GFR(mL/min/1.73 m2) | 0.927 | 0.926 | 0.928 | 0.922 | 0.92 | 0.925 | 0.972 | 0.971 | 0.973 | 0.975 | 0.973 | 0.976 |
 O3 (ppb) | 1.049 | 1.044 | 1.054 | 1.023 | 1.013 | 1.033 | 1.015 | 1.01 | 1.019 | 1.048 | 1.04 | 1.057 |
 NO2(ppb) | 1.017 | 1.013 | 1.02 | 0.992 | 0.983 | 1.001 | 1.006 | 1.003 | 1.01 | 1.019 | 1.012 | 1.026 |
Model3 | ||||||||||||
 Age | 0.987 | 0.986 | 0.989 | 0.987 | 0.984 | 0.989 | 1.06 | 1.058 | 1.062 | 1.051 | 1.048 | 1.054 |
 Male | 1.219 | 1.168 | 1.272 | 1.191 | 1.096 | 1.295 | 1.594 | 1.527 | 1.664 | 1.678 | 1.56 | 1.806 |
 Hypertension | 0.926 | 0.883 | 0.971 | 0.786 | 0.712 | 0.867 | 1.074 | 1.027 | 1.124 | 1.538 | 1.428 | 1.657 |
 Diabetic Mellitus | 1.676 | 1.603 | 1.753 | 1.675 | 1.537 | 1.825 | 1.269 | 1.215 | 1.325 | 1.168 | 1.085 | 1.258 |
 BMI < 18.5 | 0.493 | 0.462 | 0.526 | 0.452 | 0.396 | 0.514 | 0.912 | 0.865 | 0.961 | 1.014 | 0.929 | 1.106 |
 23 ≤ BMI < 25 | 0.843 | 0.795 | 0.895 | 0.893 | 0.794 | 1.003 | 0.662 | 0.622 | 0.705 | 0.633 | 0.57 | 0.702 |
 25 \(\le\) BMI | 0.778 | 0.737 | 0.821 | 0.865 | 0.779 | 0.962 | 0.601 | 0.566 | 0.638 | 0.461 | 0.414 | 0.513 |
 e-GFR(mL/min/1.73 m2) | 0.927 | 0.926 | 0.928 | 0.922 | 0.92 | 0.925 | 0.972 | 0.971 | 0.973 | 0.975 | 0.973 | 0.977 |
 O3 (ppb) | 1.049 | 1.044 | 1.054 | 1.025 | 1.014 | 1.035 | 1.012 | 1.008 | 1.017 | 1.04 | 1.031 | 1.05 |
 NO2(ppb) | 1.016 | 1.012 | 1.02 | 0.991 | 0.982 | 1 | 1.004 | 1 | 1.008 | 1.025 | 1.018 | 1.033 |
 Beds in medical facilities per 1,000 people | 1.003 | 0.997 | 1.01 | 1.012 | 1 | 1.025 | 0.979 | 0.973 | 0.985 | 0.992 | 0.982 | 1.002 |
 Financial independence | 1.001 | 1 | 1.003 | 1 | 0.997 | 1.003 | 0.999 | 0.998 | 1.001 | 0.995 | 0.992 | 0.998 |