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Fig. 5 | BMC Nephrology

Fig. 5

From: ITGAM-mediated macrophages contribute to basement membrane damage in diabetic nephropathy and atherosclerosis

Fig. 5

ITGAM influences the expression of genes encoding major components of the basement membrane. A Comparison of expression levels of genes encoding major basement membrane components between AS and normal tissues. B Comparison of expression levels of genes encoding major basement membrane components between DN tubulointerstitium and normal control. C Comparison of expression levels of genes encoding major basement membrane components between DN glomerulus and normal control. D Heatmap representing the expression levels of genes encoding major components of the basement membrane in ITGAM high-expression and low-expression groups in DN glomerulus, DN tubulointerstitium, and AS. E Correlation analysis of COL4A5, COL4A6, LAMC1, and NID2 with ITGAM in DN glomerulus. F Correlation analysis of COL4A1, COL4A2, COL18A1, and NID2 with ITGAM in DN tubulointerstitium. G Correlation analysis of COL4A1, COL4A2, LAMC1, HSPG2, COL18A1, NID1, and NID2 with ITGAM in AS

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