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Table 1 Characteristics of participants by number of Ideal Cardiovascular Health Metrics

From: Association of the combination of obstructive sleep apnea risk and sleep duration with ideal cardiovascular health metrics in patients undergoing hemodialysis

Variables

Total (n = 470)

Poor (0–2)

(n = 88)

Intermediate (3–4) (n = 273)

Ideal (5–7)

(n = 109)ref

P-value

Age, y

59.48 ± 12.89

60.39 ± 12.58

60.33 ± 12.89*

56.61 ± 12.84

0.029

BMI, kg/m2

23.14 ± 3.53

25.31 ± 3.66*

22.96 ± 3.48*

21.85 ± 2.70

<0.001

Male, n(%)

281(59.8)

75(85.2)*

169(61.9)*

37(33.9)

<0.001

Educational level, n(%)

    

0.493

 0 year

18(3.8)

1(1.1)

13(4.8)

4(3.7)

 

 1–6 years

81(17.3)

11(12.5)

49(18.0)

21(19.3)

 

 7–9 years

165(35.2)

37(42.0)

90(33.1)

38(34.9)

 

 >9 years

206(43.7)

39(44.3)

121(44.1)

46(42.2)

 

Widowed, n(%)

34(7.2)

2(2.3)

23(4.9)

9(8.3)

0.132

Living alone, n(%)

28(6.0)

6(6.8)

14(5.1)

8(7.4)

0.652

Job category, n(%)

    

0.030

 Manual work

137(29.1)

29(33.0)

77(28.2)

31(28.7)

 

 Non-manual work

192(40.9)

26(29.5)

110(40.3)

56(51.8)

 

 Mixed work

141(30.0)

33(37.5)

86(31.5)

22(20.4)

 

Drinker, n(%)

56(11.9)

16(18.2)*

33(12.1)*

7(6.4)

0.040

Smoker, n(%)

97(20.6)

31(35.2)*

62(22.7)*

4(3.7)

<0.001

Fluid overload, n(%)

247(52.6)

50(56.8)*

128(27.2)*

68(62.4)

0.019

MIS,score

3.80 ± 2.40

3.62 ± 2.39

3.83 ± 2.43

3.86 ± 2.37

0.755

CCI, score

3.23 ± 1.34

3.42 ± 1.36

3.23 ± 1.41

3.08 ± 1.11

0.214

IPAQ, Met/wk

1386(693,3465)

693(396,1386)*

1386(693,3251)*

3238(1569, 5656)

<0.001

Sp Kt/v

1.40 ± 0.32

1.32 ± 0.38*

1.39 ± 0.31

1.47 ± 0.27

0.006

Blood biochemical indexes

    

 SBP,mmHg

152.74 ± 25.46

156.61 ± 21.77*

153.58 ± 25.58

147.58 ± 27.30

0.033

 DBP, mmHg

84.23 ± 16.09

82.05 ± 16.94

85.09 ± 15.64

83.82 ± 16.44

0.292

 TCH, mmol/L

3.97 ± 1.30

3.82 ± 1.05

4.05 ± 1.47

3.91 ± 0.98

0.305

 TG, mmol/L

1.81 ± 1.49

2.93 ± 2.91

2.54 ± 8.08

1.81 ± 1.49

0.434

 LDL, mmol/L

2.34 ± 0.80

2.23 ± 0.61

2.37 ± 0.86

2.34 ± 0.77

0.345

 HDL, mmol/L

0.97 ± 0.28

0.85 ± 0.30*

0.98 ± 0.28

1.03 ± 0.26

<0.001

 GLU, mmol/L

7.50 ± 3.55

9.54 ± 4.26*

7.52 ± 3.42*

5.78 ± 2.03

<0.001

 Hemoglobin, g/L

111.70 ± 15.97

109.68 ± 15.89

112.63 ± 16.31

111.01 ± 15.10

0.282

 Albumin, g/L

40.44 ± 14.03

39.39 ± 3.04

39.88 ± 3.23

42.72 ± 28.53

0.149

 CRP, mg/L

6.18 ± 14.06

6.92 ± 12.57

5.82 ± 12.31

6.49 ± 18.87

0.816

 BUN, mmol/L

25.87 ± 6.49

25.93 ± 7.57

25.72 ± 6.45

26.20 ± 5.65

0.805

 Scr, µmoI/L

1012 ± 274

1069 ± 332

1004 ± 266

984 ± 233

0.074

 UA, µmoI/L

450.25 ± 96.91

458.69 ± 106.02

449.51 ± 97.24

444.92 ± 88.15

0.648

 Phosphate, mmol/L

1.97 ± 0.82

2.24 ± 0.22

2.58 ± 5.34

2.29 ± 0.24

0.415

 Potassium, mmol/L

4.88 ± 0.83

4.62 ± 0.76

4.88 ± 0.84

5.07 ± 0.80

0.003

 Total calcium, mmol/L

2.45 ± 4.07

2.24 ± 0.22

2.58 ± 5.34

2.29 ± 0.24

0.712

Sleep characteristic

Sleep duration

    

0.004

 <7 h

215(45.7)

56(63.6)*

115(42.1)

44(40.4)

 

 7-9 h

207(44.0)

25(28.4)*

126(46.2)

56(51.4)

 

 >9 h

48(10.2)

7(8.0)

32(11.7)

9(8.3)

 

NOA

1.64 ± 1.36

1.65 ± 1.46

1.73 ± 1.37

1.40 ± 1.25

0.107

Sleep mediation, n(%)

111(23.6)

23(26.1)

66(24.2)

22(20.2)

0.586

Sleep quality, n(%)

    

0.056

 Very well

142(30.2)

18(20.5)

90(33.0)

34(31.2)

 

 Good

188(40.0)

35(39.8)

105(38.5)

48(44.0)

 

 Not enough

64(13.6)

20(22.7)*

35(12.8)*

9(8.3)

 

 Very poor

76(16.2)

15(17.0)

43(15.8)

18(16.5)

 

OSA risk, n(%)

234(49.8)

64(72.7)

135(49.5)

35(32.1)

<0.001

  1. Data are mean ± SD, percentage or median (quartile 1, quartile 3)
  2. P-value comparison across number of cardiovascular health metrics groups using analysis of variance or Kruskal-Wallis for continuous variables and χ2 test for qualitative variables
  3. *p < 0.05, compared with subjects with ideal cardiovascular health metrics (5–7)
  4. Abbreviations: BMI, body mass index; MIS, malnutrition inflammation score; CCI, charlson comorbidity index; IPAQ, international physical activity questionnaire; Sp Kt/v,single-pool Kt/V-urea; SBP,systolic blood pressure; DBP,diastolic blood pressure; TCH,total cholesterol; TG,triglycerides; LDL,low density lipoprotein cholesterol; HDL,high density lipoprotein cholesterol; GLU, glucose; CRP,C-reactive protein; BUN,blood urea nitrogen; Scr,serum creatinine;UA,uric acid;NOA,number of awakenings; OSA,obstructive sleep apnea