Table 1 Comparison of cellular immune indices between the PMN group and the healthy group
From: Rituximab may affect T lymphocyte subsets balance in primary membranous nephropathy
Healthy Group (n = 25) | PMN Group (n = 58) | Z | P | |
|---|---|---|---|---|
CD3+T, cells/µl | 1025.29(784.13, 1293.04) | 1234.04(1019.45, 1635.95) | -1.975 | 0.048 |
CD3+CD4+T, cells/µl | 659.25(558.13, 867.24) | 836.30(679.06, 1049.29) | -2.392 | 0.017 |
CD4+central memory T, cells/µl | 141.39(107.10, 188.80) | 261.62(176.00, 351.60) | -4.298 | < 0.001 |
CD4+effect memory T, cells/µl | 231.51(201.07, 268.57) | 290.32(187.13, 388.35) | -4.729 | < 0.001 |
CD4+CD25+T, cells/µl | 2.44(1.12, 3.39) | 21.91(7.73, 34.79) | -5.499 | < 0.001 |
CD4+CD25+CD127loT (Treg), cells/µl | 37.74(22.10, 61.15) | 18.67(10.68, 34.35) | -3.861 | < 0.001 |
CD3+CD8+T, cells/µl | 517.92(320.26, 612.81) | 285.55(195.48, 423.27) | -3.325 | 0.001 |
CD8+central memory T, cells/µl | 27.87(8.57, 38.69) | 11.14(6.66, 19.19) | -2.293 | 0.022 |
CD8+effect memory T, cells/µl | 191.30(121.39, 268.35) | 100.73(71.39, 184.87) | -2.710 | 0.007 |
CD8+CD25+T, cells/µl | 1.49(0.28, 7.16) | 1.43(0.28, 7.88) | -0.178 | 0.858 |
CD4+/CD8+ | 1.46(1.06, 2.39) | 2.73(1.84, 4.61) | -4.065 | < 0.001 |
CD3+CD4-CD8-T, cells/µl | 104.70(57.63, 144.02) | 103.17(53.39, 168.13) | -0.238 | 0.812 |
CD16+CD56+NK, cells/µl | 201.87(160.84, 289.20) | 238.21(195.31, 438.86) | -1.122 | 0.262 |